Recent in Testing (page 25 of 26)

Mechanisms of Tape Stripping and Protein Quantification

In this article, several methods to quantify the protein collected by tape stripping are described, including traditional gravimetric methods as well as novel colorimetric and visible spectroscopic techniques. Further, one colorimetric method is described to effectively determine the keratolytic efficacy of various materials in vivo, suggesting additional roles for this method.

Microfluidic Testing for LLNA Replacement

The Hurel Corp. has developed a microfluidic, non-animal alternative to the LLNA and it has partnered with L’Oréal to make this approach a reality—in the form of a chip.

A Rapid and Sensitive In vitro Method to Ascertain Antioxidative Capacity*

New methodologies have recently been developed to determine antioxidant effects but they often require extensive training and are time-consuming to conduct. In the present article, however, the authors describe an in vitro method to detect the effects of antioxidant-containing formulations using photochemiluminescence to provide rapid, accurate and sensitive measurements.

Researchers Mimic the Lymphatic System in Animal Alternative Chip

A chip created by L'Oréal and Hurel Corp. is designed to replace the local lymph node assay, a test often performed on cosmetic raw materials. In addition to saving animals, the chip is also said to be less expensive than animal testing. Hurel developed the working microfluidic portion of the chip.

Updated Modeling and Simulation Platform for Chemists

A new software platform has been designed to improve the efficiency and effectiveness of chemical and materials research to increase research productivity and decrease time-to-innovation.

Webinar Focused on Cell-based Assays

BD Biosciences is hosting a webinar dedicated to cell-based assays. Elizabeth Abraham, PhD, a research scientist at BD Biosciences, will discuss the applications for the company's BD PureCoat surfaces.

In the Land of the Blind: Applying a Single-blind Study to Finished Products

Following positive feedback from a previous column on the placebo effect, Wiechers readdresses clinical study design in relation to cosmetic claim substantiation—this time discussing when to perform double-blind studies and when to perform single-blind studies.

Genetic Test for Alopecia Approved in Europe

The HairDX Genetic Test for Hair Loss, a genetic baldness test manufactured by HairDX LLC, is now available as a CE Marked product under the European In Vitro Diagnostic Directive.

Falling Ball Viscometer for Newtonian Fluid Measurement

Brookfield Engineering celebrates its 75th anniversary with the introduction of the Falling Ball Viscometer, an instrument to assess the dynamic viscosity of transparent Newtonian fluids.

Characterizing Roughness: A New Substrate to Measure SPF

Here, the authors describe a variable that affects the results of SPF testing in vitro—the roughness parameter—and investigate this variable using standard and molded poly(methyl methacrylate) (PMMA) substrates. They conclude that use of a molded substrate, along with the described control chart, improves the reproducibility of in vitro SPF test results.

ECVAM Calls for Testing Experts

The European Centre for the Validation of Alternative Methods (ECVAM) is renewing its scientific advisory structure and is calling for life sciences experts interested in joining its ESAC or EEP groups.

Virtually Real

This edition of C&T magazine takes a closer look at alternatives to animal testing with Oborska’s review of existing and pending methods. In addition, the author discusses the complexity of the process to validate alternative test methods.

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