Recent in Testing (page 24 of 26)

Interpretation of SPF In vivo Results: Analysis and Statistical Explanation

Methods for determining SPF in vivo are based on a biological response by human skin. To overcome intrinsic variation in these methods, large numbers of volunteers and statistics are required; however, these concepts are often poorly understood or worse, misinterpreted. This article discusses how these values should be interpreted and explains what they mean to formulators.

Adapting SPF Testing Methods for Mineral Sunscreen Density

A sunscreen layer’s thickness is critical to its SPF. However, current regulations specify a mass application rate for testing, rather than a volumetric application rate. This significantly underrates the SPF values of mineral sunscreens due to their higher densities since, compared with their relative organic counterparts, thinner films are being tested, as will be shown here.

Researcher Develops Probe for Non-invasive Below Skin Imaging

Jannick Rolland, PhD, an optics professor at the University of Rochester in New York, has developed an optical probe equipped with a liquid lens that takes images under the skin’s surface without the use of invasive procedures.

ICCVAM and NICEATM Hold Meeting on Endocrine Disruptor Test Method

ICCVAM and NICEATM will hold a peer review meeting on March 29-30, 2011, for an in vitro test method that determines if chemicals are endocrine disruptors.

A Review of Genomic Techniques in Cosmetics Testing

Genomics assists product developers in understanding the expression of specific genes and their relationship to particular skin attributes. This article reviews commonly used testing techniques, such as DNA microarray, RT-PCR, SAGE, northern blot and RNA sequencing, and describes their application in testing the effects of cosmetic ingredients and products on skin.

ISO Equips Formulators to Identify Low-risk Cosmetic Products

The International Organization for Standardization (ISO) has released an international standard that will assist the cosmetic industry in identifying those products that have a low potential for contamination.

Evaluating the Physiochemical Properties of Emollient Esters for Cosmetic Use

This study assesses the physicochemical properties of four known cosmetic emollient esters in vitro to predict their sensorial benefits and correlate their properties with in vivo sensory attributes. This evaluation serves as a guide to selecting specific emollient esters for various cosmetic applications and to predicting their sensory attributes.

Fluorescence Laser Scanning Confocal Microscopy to Assess the Penetration of Low Molecular Protein Hydrolyzates Into Hair

The present study uses confocal laser scanning fluorescence microscopy to assess the penetration of protein hydrolyzates into hair. While higher amounts of protein were found in the cuticle, still significant quantities were observed in the cortical parts of hair, and this penetration was enhanced by longer incubation times.

Paper Posted to Aid Manufacturers with Harmonized Microbial Testing

Microtest Laboratories has posted a white paper on its website to help personal care product manufacturers understand microbial limits testing policies in accordance with the harmonization of the United States Pharmacopeia (USP), European Pharmacopeia (EP) and Japanese Pharmacopeia (JP) requirements.

ICCVAM Recommends Ocular Safety Tests for Cosmetics and Other Products

Four test method evaluation reports are now available from ICCVAM that provide recommendations for performing eye safety testing more humanely, and for developing and using non-animal test methods and strategies. Among these reports, ICVAAM has recommended that a cytosensor microphysiometer (CM) test method may be used to screen surfactant-containing formulations such as personal care products for the ability to cause permanent or severe eye injuries.

Antiaging in a Different Light: Assessing How Chromophores Color Perception

Aging influences cutaneous parameters that give rise to progressive changes in three skin chromophores, altering the visual homogeneity of skin. To address these changes, the authors developed and examined the effects of a complex based on Siegesbeckia orientalis and Rabdosia rubescens using a novel skin imaging technique.

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