Testing

Recent in Testing (page 24 of 32)

DB-ALM Creates Database of Animal Alternative Subscribers

The Database on Alternative Methods (DB-ALM) now offers the public a directory of individuals and institutions that are active in the field of animal-alternative testing methods .

REACH and In Vitro Alternatives: Phototoxicity Testing

This is the third column in a continuing discussion regarding the new REACH regulations and their impact on chemical testing. The first appeared in December 2007 and discussed dermal corrosive potential testing; the second, in February 2008, covered dermal irritancy potential testing.

Molecular Modeling of Skin care Products: Application for the Design of Pepidomimetics

Molecular modeling has been used in the pharmaceutical industry for years to predict how a new molecule may work based on research conducted with molecules of a similar structure. The cosmetics industry has also begun to use this technology to predict the behavior of new molecules on skin and in skin care applications.

Using Ultrasound Scanning to Characterize Colloidal Particles

Changes in the macroscopic nature of aqueous or colloidal formulations can lead to changes in the odor, appearance or feel of a product. Data presented in this article demonstrates ultrasound scanning to determine formulation shelf life and monitor product quality.

Analytical Device Raises the Bar on UVA-PF

A new UV transmittance analyzer has been designed to exceed Colipa's UVA protection factor (UVA-PF) requirements to support the development of higher protection factor sunscreens.

Domo Arigato, Mr. Roboto: Robots to Reduce Animal Testing

The National Institute of Health (NIH) is collaborating with the Enviromental Protection Agency (EPA) to improve the safety testing of chemicals. Both agencies have agreed to a new toxicity testing agreement to reduce reliance on animal testing.

Three Decades of Patch Testing: Trends in the North American Populace

This report evaluates the trends in the results of patch testing. The patch test reactions were surveyed retrospectively. The results were statistically compared between 1970 and 2002 because appropriate interpretation of the numbers has public health opportunities.

ICCVAM Creates Five Year Plan

The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) has created a five year plan to reduce, refine and replace the use of animals in research and product testing.

Testing Tactics: REACH and In vitro Alternatives: Skin Irritation Testing

Welcome back to a continuing discussion regarding the new Registration, Evaluation and Authorization of Chemicals (REACH) regulation and its impact on chemical testing. It is the purpose of this series of articles to provide an overview of these existing validated in vitro methods, as well as new methods that are being considered for validation.

Texture Analysis to Quantify Skin Care Product Efficacy

Using a texture analyzer to measure the tightness of the skin before and after the application of selected treatments, the authors demonstrate the potential of texture analysis instrumentation in testing the efficacy of skin care products and substantiating skin tightening claims.

In Sight—QOL Testing: Complementing Clinicals

Personal care efficacy tests are known to test the physical effects or toxicity of products, often omitting more abstract and possibly equally as important factors such as well-being.

A Dermatological View: Tandem Irritants With Synergistic, Additive or Quenching Effects on the Skin

In this article the results of six published tandem irritation studies are evaluated; possible mechanisms and clinical ramifications, albeit complex, are discussed. The clinical relevance of tandem irritation among cosmetics users and in many occupational settings appears obvious and suggests the need for further studies clarifying its principles and mechanisms.

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