Recent in Testing (page 24 of 31)

Testing Tactics: REACH and In vitro Alternatives: Skin Irritation Testing

Welcome back to a continuing discussion regarding the new Registration, Evaluation and Authorization of Chemicals (REACH) regulation and its impact on chemical testing. It is the purpose of this series of articles to provide an overview of these existing validated in vitro methods, as well as new methods that are being considered for validation.

Texture Analysis to Quantify Skin Care Product Efficacy

Using a texture analyzer to measure the tightness of the skin before and after the application of selected treatments, the authors demonstrate the potential of texture analysis instrumentation in testing the efficacy of skin care products and substantiating skin tightening claims.

In Sight—QOL Testing: Complementing Clinicals

Personal care efficacy tests are known to test the physical effects or toxicity of products, often omitting more abstract and possibly equally as important factors such as well-being.

A Dermatological View: Tandem Irritants With Synergistic, Additive or Quenching Effects on the Skin

In this article the results of six published tandem irritation studies are evaluated; possible mechanisms and clinical ramifications, albeit complex, are discussed. The clinical relevance of tandem irritation among cosmetics users and in many occupational settings appears obvious and suggests the need for further studies clarifying its principles and mechanisms.

Biochip Takes the Next Step Toward Replacing Animal Testing

Researchers at Rensselaer, the University of California-Berkeley, and Solidus Biosciences Inc. have developed a biochip that can mimic the effects of metabolism and analyze materials for toxicity.

Testing Tactics—REACH and In vitro Alternatives: Corrosive Potential Testing

The authors of the REACH directive had the foresight to recognize the impact of such a large amount of testing on animal use and mandated that in vitro testing methods should be used as animal testing alternatives whenever possible.

Rheological Characterization of a Modified Taurate Acrylic Polymer for Skin Care

The rheology of a pre-neutralized, hydrophobically modified acrylic polymer was investigated by dynamic mechanical measurements using this methodological approach to establish its viscoelastic profile and stability in formulations. Properties of several polymer-containing emulsions were studied and their particle size distribution investigated by laser diffraction.

Ex Vivo Porcine Developed as Alternative to Animal Testing

Symrise and Cutech Srl have developed a new skin model out of pig skin as an alternative to animal testing.

Alternative Testing or Testing Alternatives?

Johann Wiechers, PhD, writes: I am driving in a taxi somewhere with a female colleague when she asks me an intriguing question. “Tell me, Johann, how would you measure breast firming?”

Compass: Direct Routes

Will a flourishing category ever chance revealing this truth behind naturals to consumers? Perhaps so, as the naturals market becomes more saturated and key manufacturers seek ways to drive consumer interest into new areas.

Using Consumers’ Sensory Experience to Achieve Strategic Market Segmentation

Used in conjunction with marketing and marketing research techniques, consumer-based sensory evaluation techniques provide an effective business strategy for product development and brand management.

Computer-aided Formulating

Informatics techniques have been developed that are capable of manipulating huge data sets that underpin modern formulation—from mining for information, to analyzing vast amounts of data. This article highlights how the use of computer technology can increase the efficiency and efficacy of formulating.

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