Recent in Testing (page 19 of 31)

Paper Posted to Aid Manufacturers with Harmonized Microbial Testing

Microtest Laboratories has posted a white paper on its website to help personal care product manufacturers understand microbial limits testing policies in accordance with the harmonization of the United States Pharmacopeia (USP), European Pharmacopeia (EP) and Japanese Pharmacopeia (JP) requirements.

ICCVAM Recommends Ocular Safety Tests for Cosmetics and Other Products

Four test method evaluation reports are now available from ICCVAM that provide recommendations for performing eye safety testing more humanely, and for developing and using non-animal test methods and strategies. Among these reports, ICVAAM has recommended that a cytosensor microphysiometer (CM) test method may be used to screen surfactant-containing formulations such as personal care products for the ability to cause permanent or severe eye injuries.

Antiaging in a Different Light: Assessing How Chromophores Color Perception

Aging influences cutaneous parameters that give rise to progressive changes in three skin chromophores, altering the visual homogeneity of skin. To address these changes, the authors developed and examined the effects of a complex based on Siegesbeckia orientalis and Rabdosia rubescens using a novel skin imaging technique.

Tools to Predict, Assess and Standardize Successful Color Cosmetics

Cosmetic companies have borrowed quality control methods from other industries that have product attributes such as color, gloss and texture down to a science. Specialized in such areas, X-Rite has developed tools to enable cosmetic companies to predict future color trends as well as set standards by which future cosmetics will be benchmarked.

Skin Toxicology—The Future May Be Orange

Here, industry expert Johann Wiechers, PhD, discusses the frequent use of percentages by toxicologists to calculate skin penetration. To relate this discussion to modern day events, Wiechers describes the skin penetration of orange paint, used by fans of the Dutch national football team.

TRI/Princeton Offers Hair Benchmarking Study to Share Testing Costs

This benchmarking study allows manufacturers to test hair products for conditioning, anti-breakage strengthening, and anti-static flyaway reduction with shared controls and labor to reduce costs by up to 57%. The company is accepting participants until Aug. 15, 2010.

CeeTox Expands In Vitro Capabilities with Acquisition

CeeTox has acquired assets of ADMETRx Inc. that allow it to expand its range of in vitro service offerings. Specifically, the acquired assets allow CeeTox to increase its existing Absorption, Distribution, Metabolism, Excretion (ADME) capabilities.

Researchers Advance Animal-alternate Test for Skin Sensitization

Researchers at the National Institute for Occupational Safety and Health and Portland State University have developed an animal-alternative test method to assess the potential for chemicals in consumer products to cause skin allergies.

Evaluating Essential Oils in Cosmetics: Antioxidant Capacity and Functionality

In the present work, the antioxidant capacities of three essential oils derived from basil and thyme were evaluated using a photochemiluminescence (PCL)-based assay. In addition, since the base formulation can affect the antioxidant activity of oils contained therein, ingredient interactions within final formulations were investigated.

Evaluating 1,3-Propanediol for Potential Skin Effects

In the present article, the authors assess the skin irritation and sensitization potential of 1,3-propanediol (INCI: Propanediol). Results in animals and humans by acute or repeat exposure support a low potential of skin reactivity for the material. In addition, the skin reactivity potential in humans was found to be lower with 1,3-propanediol than 1,2-propanediol (INCI: Propylene Glycol).

Predicting the Percutaneous Penetration of Cosmetic Ingredients

While previous algorithms for predicting the skin absorption of permeants was based on in vitro data, the present article proposes a quantitative structure-activity relationship (QSAR) model based on in vivo human data. Here, a set of human in vivo data is described that provides entry into predicting the penetration of cosmetic ingredients.

Is Cosmetic Science Really "Bad"? Part IV: How Scientific is Cosmetic Science?

Six questions from Michael Shermer’s Baloney Detection Kit have been discussed in this series. The results were not flattering for cosmetic science (read: cosmetic scientists) but cosmetic science did not score badly on all points. Questions seven and eight, described here, discriminate true science from borderland science and non-science or nonsense.

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Practical Modern Hair Science

Practical Modern Hair Science

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  • Science of hair color including chemical reactions and formulations
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Apply Topically: A Guide to Formulating

Apply Topically: A Guide to Formulating

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