Recent in Testing (page 16 of 21)

Evaluating Water Permeability and Occlusion in Wound Dressings and Topical Cosmetics

The present study uses an evaporimeter to measure the degree of water loss from in vitro skin samples covered by occlusive and semi-occlusive wound dressings to serve as a model for determining the effectiveness of occlusive cosmetic formulations. The purpose of this work was to develop a model for determining the effectiveness of occlusive cosmetic formulations.

DNA: Hard Evidence of Cosmeceutical Claims

To support finished product or raw material claims these two in vitro methods—the Affymetrix microarray and the Taqman Real Time Polymerase Chain Reaction (PCR)—measure the up-regulation or down-regulation of genes.

In Vitro Model for Decontamination of Human Skin

The present study utilized an in vitro model to compare the decontamination capacity of three model decontaminant solutions: tap water, isotonic saline and hypertonic saline. Human cadaver skin samples were dosed with radio-labeled [14C]-formaldehyde and the surface skin of each sample was washed after each exposure with one of the three model decontaminant solutions.

Fluid Skin Imaging for Better Resolution

Noninvasive subcutaneous skin imaging is a tool sought for use by the medical, pharmaceutical and personal care industries, but techniques have been lacking due to resolution and speed constraints.

Interpretation of SPF In vivo Results: Analysis and Statistical Explanation

Methods for determining SPF in vivo are based on a biological response by human skin. To overcome intrinsic variation in these methods, large numbers of volunteers and statistics are required; however, these concepts are often poorly understood or worse, misinterpreted. This article discusses how these values should be interpreted and explains what they mean to formulators.

Adapting SPF Testing Methods for Mineral Sunscreen Density

A sunscreen layer’s thickness is critical to its SPF. However, current regulations specify a mass application rate for testing, rather than a volumetric application rate. This significantly underrates the SPF values of mineral sunscreens due to their higher densities since, compared with their relative organic counterparts, thinner films are being tested, as will be shown here.

Evaluating the Physiochemical Properties of Emollient Esters for Cosmetic Use

This study assesses the physicochemical properties of four known cosmetic emollient esters in vitro to predict their sensorial benefits and correlate their properties with in vivo sensory attributes. This evaluation serves as a guide to selecting specific emollient esters for various cosmetic applications and to predicting their sensory attributes.

Fluorescence LSCM to Assess the Penetration of Low Molecular Protein Hydrolyzates Into Hair

The present study uses confocal laser scanning fluorescence microscopy to assess the penetration of protein hydrolyzates into hair. While higher amounts of protein were found in the cuticle, still significant quantities were observed in the cortical parts of hair, and this penetration was enhanced by longer incubation times.

A Review of Genomic Techniques in Cosmetics Testing

Genomics assists product developers in understanding the expression of specific genes and their relationship to particular skin attributes. This article reviews commonly used testing techniques, such as DNA microarray, RT-PCR, SAGE, northern blot and RNA sequencing, and describes their application in testing the effects of cosmetic ingredients and products on skin.

Fischer-Tropsch vs. Mineral Products for Moisturization

Differing amounts of Fischer-Tropsch (FT) wax were used in petroleum jelly and final cosmetic emulsions to evaluate moisturizing effects in skin. FT wax was shown to perform as well or better than traditional mineral-derived products.

Assessing the Impact of Hair Damage Types on Color Retention

This article reviews and assesses damage types caused to hair before and after artificial coloration, i.e., by bleaching, perming, heat treatment, UV exposure and shampooing, to compare how they impact color durability individually and combined. Formulation emerges as the key to designing shampoos that efficiently deliver actives to improve color protection against these and other damage types.

Comparison of Age Determination by Three Evaluation Methods: Self-assessment, Expert Grader and Naïve Grader

This exploratory study investigates how consumers perceive age, using objective and subjective approaches. Results of this study suggest that when a subjective approach is implemented for age determination, subjects affix their emotions to the evaluation. The reverse logic was applicable for the expert and naïve grader methods, as grader results appeared more neutral than the self-assessment.

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