Recent in Testing (page 14 of 31)

A Rapid and Sensitive In vitro Method to Ascertain Antioxidative Capacity*

New methodologies have recently been developed to determine antioxidant effects but they often require extensive training and are time-consuming to conduct. In the present article, however, the authors describe an in vitro method to detect the effects of antioxidant-containing formulations using photochemiluminescence to provide rapid, accurate and sensitive measurements.

Researchers Develop Non-animal, Dendritic-based Sensitizer Test

Researchers from the University of Aveiro, the University of Coimbra and the University Hospital of Coimbra have developed a dendritic cell-based test for skin sensitizers that can serve as an alternative to animal testing.

Beiersdorf Researcher Develops Skin Imaging Method for Analysis

Beiersdorf has created a new method of skin analysis to help it develop new skin care products.

A High Throughput Method to Predict Skin Penetration and Screen Topical Formulations

This work studies the applicability of a 96-well-based skin-mimetic artificial membrane permeability model to differentiate between topical pharmaceutical and cosmetic formulations. Results are compared with data obtained from in vitro Franz cell permeability measurements and reveal the applicability of this method to assess cosmetic formulation permeation and speed the discovery process.

Influence of Skin Diffuse Reflectance on Sun Damage and Ingredient Efficacy Measurements

Current in vitro methods to assess photostability and antioxidant activity do not account for the diffuse reflectance of skin. Described here is an in vitro test that addresses this variable, mimics end-use product conditions and models photodamage processes. The approach is employed to determine the efficacy of an antioxidant from the Camellia sinensis (tea) plant.

Hair Ethnicity and Ellipticity: A Preliminary Study

Ethnic hair care addresses diverse fiber compositions that require unique products. This comprehensive review in hair fiber dimensions among straight, wavy and curly/coily hair serves as a basis from which product developers can design products to cater to unique hair type needs. The current study examines the ellipticity of Caucasian, Brazilian, Hispanic and African-American hair.

Hair Ethnicity and Ellipticity: A Preliminary Study

Ethnic hair care addresses diverse fiber compositions that require unique products. This comprehensive review in hair fiber dimensions among straight, wavy and curly/coily hair serves as a basis from which product developers can design products to cater to unique hair type needs. The current study examines the ellipticity of Caucasian, Brazilian, Hispanic and African-American hair.

Adjusting Substrate/Product Interfacial Properties to Improve In vivo/In vitro SPF Correlation

This work evaluates the impact of a plasma treatment on test substrates to modify their surface energy, to more closely correlate in vitro SPF measurements with in vivo measurements—without chemically altering the test products. The authors chose the level of plasma modification to use on a substrate based on in vivo values; they explain how to choose it regarding specific formulas in a further paper.

The Effect of Skin Metabolism on the Absorption of Chemicals

Skin expresses enzymes that can metabolize endogenous molecules but little is known regarding how they impact the delivery of xenobiotics. This review of recent works shows that skin metabolism alters the dermal absorption of lipophilic compounds, which opens new areas of investigation regarding the safety and efficacy of topically applied cosmetics.

Scalp Irritation From Hair Care Chemicals

While scalp irritation also can be caused by contact with physical or biological agents, this column will discuss the irritation resulting from hair chemicals. The desire for a specific hairstyle or color can render the scalp exposed to different hair chemicals that may result to scalp irritation.

A High Throughput Method to Predict Skin Penetration and Screen Topical Formulations

This work studies the applicability of a 96-well-based skin-mimetic artificial membrane permeability model to differentiate between topical pharmaceutical and cosmetic formulations. Results are compared with data obtained from in vitro Franz cell permeability measurements and reveal the applicability of this method to assess cosmetic formulation permeation and speed the discovery process.

Influence of Skin Diffuse Reflectance on Sun Damage and Ingredient Efficacy Measurements

Current in vitro methods to assess photostability and antioxidant activity do not account for the diffuse reflectance of skin. Described here is an in vitro test that addresses this variable, mimics end-use product conditions and models photodamage processes. The approach is employed to determine the efficacy of an antioxidant from the Camellia sinensis (tea) plant.

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Practical Modern Hair Science

Practical Modern Hair Science

Between The Covers Discover:

  • Amino acid distribution and biochemistry
  • Examination of strength and anti-breakage product claims
  • Hair: growth cycle, heat protection, shine, and color intensity and retention
  • Overview of shampoos and issues relating to surfactants
  • Science of hair color including chemical reactions and formulations
  • Ethnic differences in hair and absorption of materials
  • Evaluate and quantify visual properties of hair
  • Dandruff-Causes and biology of the condition
  • Hair styling products and polymers

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Apply Topically: A Guide to Formulating

Apply Topically: A Guide to Formulating

Finally! This book offers practical approach to the formulation chemist’s day-to-day endeavors by: addressing the innumerable challenges facing the chemist both in design and at bench, such as formulating with/for specific properties; offering valuable “tips” to troubleshooting issues regarding ingredient selection and interaction, regulatory concerns that must be addressed early in development, and the extrapolation of preservative systems; exploring the advantages and limitations of raw materials; addressing scale-up and pilot production process and concerns; and much more.Order your copy today.