Recent in Testing (page 10 of 31)

Mature and Immature Corneocyte Detection Force Distance Curves vs. Microfluorometry

Here, the author compares two methods to determine the maturity of corneocytes based on their cross-linking that could be used to evaluate the anti-aging effects of molecular agents. The first utilizes microfluorometry, while the second involves F-D curves generated via contact mode AFM. Both methods successfully detected differences in mature or immature corneocytes with 95% confidence.

Measuring Hair Strength, Part I: Stress-Strain Curves

This article is the first in a series that will address the approaches of measuring the “strength” of hair and quantifying the manner by which this property may be altered. Specifically, it will begin with the generation of stress-strain curves through the use of constant rate extension experiments.

Testing Tactics—Consumer vs. Scientific Language: Relating In vivo to In vitro

It should perhaps go without saying that consumer products are sold using consumer language. Market researchers and consumer scientists spend a great deal of time studying their target audience and learning this vocabulary, which subsequently allows the recounting of product benefits in the same terminology.

IBN Engineers Hair Follicle Model for Development of Anti-hair loss Actives

The Institute of Bioengineering and Nanotechnology (IBN) has recently engineered a new hair follicle model that could help discover new drugs or active ingredients for hair regeneration.

Testing Tactics: REACH and In vitro Alternatives: Skin Irritation Testing

Welcome back to a continuing discussion regarding the new Registration, Evaluation and Authorization of Chemicals (REACH) regulation and its impact on chemical testing. It is the purpose of this series of articles to provide an overview of these existing validated in vitro methods, as well as new methods that are being considered for validation.

Measuring Hair Strength, Part I: Stress-Strain Curves

This article is the first in a series that will address the approaches of measuring the “strength” of hair and quantifying the manner by which this property may be altered. Specifically, it will begin with the generation of stress-strain curves through the use of constant rate extension experiments.

A Dermatological View: Tandem Irritants With Synergistic, Additive or Quenching Effects on the Skin

In this article the results of six published tandem irritation studies are evaluated; possible mechanisms and clinical ramifications, albeit complex, are discussed. The clinical relevance of tandem irritation among cosmetics users and in many occupational settings appears obvious and suggests the need for further studies clarifying its principles and mechanisms.

Evaluating Hair Conditioning with Instrumental Combing

When formulating a hair care product, there is often a need for testing that validates the product’s technical performance. This testing provides guidance to create formulas with appropriate performance, while also communicating the product’s message to the consumer. This article discusses the use of instrumental combing measurements when formulating hair conditioning products.

Significant Statistical Differences in Sensory Research

My dictionary has two definitions of the term significant. As others have pointed out, a research finding may be true without being important. When statisticians say a result is “highly significant,” they mean it is very probably true. Importance and meaning are determined by the consumer.

Characterizing Roughness: A New Substrate to Measure SPF

Here, the authors describe a variable that affects the results of SPF testing in vitro—the roughness parameter—and investigate this variable using standard and molded poly(methyl methacrylate) (PMMA) substrates. They conclude that use of a molded substrate, along with the described control chart, improves the reproducibility of in vitro SPF test results.

Alternatives to Animal Testing: A Review of Trends and Perspectives

Alternative test methods have the potential to reduce animal testing; however, the extent to which in vitro methods can be replaced is questionable. This article summarizes validated alternatives to test the safety of cosmetic ingredients. It also illustrates how great a challenge it is to devise a proper alternative method.

Rapid Colorimetric Analysis of para-Phenylenediamine in Henna-based, Non-permanent Tattoo Color Mixtures

In some henna mixtures, para-phenylenediamine (PPD) has illegally been added and it is responsible for complications such as allergic contact dermatitis. While high-performance liquid chromatography has previously been used to detect PPD, a colorimetric method that is faster and portable, described here, has been developed. For product developers, this method can be used to evaluate henna plant extracts.

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Practical Modern Hair Science

Practical Modern Hair Science

Between The Covers Discover:

  • Amino acid distribution and biochemistry
  • Examination of strength and anti-breakage product claims
  • Hair: growth cycle, heat protection, shine, and color intensity and retention
  • Overview of shampoos and issues relating to surfactants
  • Science of hair color including chemical reactions and formulations
  • Ethnic differences in hair and absorption of materials
  • Evaluate and quantify visual properties of hair
  • Dandruff-Causes and biology of the condition
  • Hair styling products and polymers

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Apply Topically: A Guide to Formulating

Apply Topically: A Guide to Formulating

Finally! This book offers practical approach to the formulation chemist’s day-to-day endeavors by: addressing the innumerable challenges facing the chemist both in design and at bench, such as formulating with/for specific properties; offering valuable “tips” to troubleshooting issues regarding ingredient selection and interaction, regulatory concerns that must be addressed early in development, and the extrapolation of preservative systems; exploring the advantages and limitations of raw materials; addressing scale-up and pilot production process and concerns; and much more.Order your copy today.