Protecting the Skin from Environmental Stresses with an Exopolysaccharide Formulation

$$item.publishDate) | Contact Author | By: A. Thibodeau, Atrium Biotechnologies
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Title: Protecting the Skin from Environmental Stresses with an Exopolysaccharide Formulation
Polysaccharidex exopolysaccharidesx hydrothermalx epidermisx ICAM-1x leucocytesx keratinocytesx interferonx fibroblastsx
  • Article
An increasing number of hyperthermophilic and mesophilic bacteria have been isolated from deep-sea hydrothermal vents throughout the past 20 years and found to be an extraordinary source of innovative molecules with unusual biological properties. These properties have developed as defense mechanisms enabling the marine organisms to adapt themselves to extreme conditions of temperature, pressure and darkness that prevail in the world’s seas.


Among these, bacteria belonging to the genus Alteromonas, and precisely to the species A. macleodii, were identifi ed as being able to produce large amounts of biologically active exopolysaccharides (EPS). A close investigation of some of these biopolymers revealed that they could be of powerful value in the cosmetic industry by providing a new way to protect the skin from environmental injuries. The best example is a polysaccharide produced by A. macleodii, strain HYD657a (EPS657) that is the sole bioactive polymer in a described Alteromonas ferment extract formulationb (SEPS657). The present review will focus on this ferment extract with particular emphasis on its properties as exemplifi ed by a number of laboratory and clinical studies. A separate article on page 26 discusses the scheme of events that led to its discovery. 

Excerpt Only This is a shortened version or summary of the article that appeared in the Dec. 1, 2005 issue of Cosmetics & Toiletries magazine. The full content is not currently available online.