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New in Function (page 8 of 51)
Dec 02, 2011 | 02:57 PM CST
Human Skin and Ocular Flora: The Effect of Product Formulation, Part 1
By: Melanie George, PhD Avon Products Inc.
This first of two articles reviews transient and resident microbial populations of the human skin and how they alter with age, environment and exposure to antimicrobial agents. Considerations for the formulator of how cosmetic products may affect and be impacted by normal human flora also are provided.
Dec 02, 2011 | 02:17 PM CST
Ethyl Lauroyl Arginate HCl for Natural Preservation
By: Maria Minguet, PhD; Rut Barcelona, MD; Eduard …
Ethyl lauroyl arginate HCl (LAE), derived from natural lauric acid and L-arginine, is shown here to provide broad-spectrum activity against microorganisms including Malassezia furfur and Propionibacterium acnes. In vitro tests corroborated by in vivo evaluations suggest its efficacy in anti-dandruff and dermo-purifying applications.
Dec 02, 2011 | 02:14 PM CST
Improving Deposition From High-water Formulas Using Amphiphilic Polymers
By: Mussarat Noor; Richard Goddard, PhD; and Arnol…
Effective high-water skin care systems may play an important role in addressing emerging market consumer needs. The present study considers the challenges of such systems, particularly regarding the deposition of ingredients across water solubilities, and proposes an amphiphilic cationic polymer as one possible solution.
Dec 02, 2011 | 02:05 PM CST
Formula Anatomy Deciphered—Shampoos
By: Eric S. Abrutyn, TPC2 Advisors Ltd.
The primary purpose of a shampoo is to clean the hair and scalp; all other attributes such as styling, conditioning split ends, adding shine and improving combability are accomplished by grooming tasks and used for claim purposes to differentiate a product from the competition.
Dec 02, 2011 | 02:00 PM CST
Ingredient Profile—Sodium Lauroamphoacetate
By: Michael J. Fevola, PhD, Johnson & Johnson
The present column features one of the oldest and most well-known members of the amphoteric family: sodium lauroamphoacetate (SLAA).
Nov 04, 2011 | 01:17 PM CDT
Pollution and Aging: Antioxidants for Skin
By: Jean-Francois Nicolay and Christophe Paillet, …
Cell membrane-derived lipidic hydroperoxides, introduced into the skin by environmental stresses, seem to be key players in oxidative stress-mediated extrinsic aging. Imidazole-containing peptidomimetics can protect against their toxicity through a variety of mechanisms.
Nov 04, 2011 | 11:05 AM CDT
What Every Formulator Needs to Know About Fragrance
By: Felix Buccellato and Christian Buccelllato, Cu…
This overview of the types of problems encountered when fragrancing personal care products discusses issues of stability, solubility, color change and compatibility of fragrance and product ingredients.
Oct 28, 2011 | 03:37 PM CDT
A New Thickener/Stabilizer Technology
By: Stephen L. Kopolow, PhD; Yoon Tae Kwak, PhD; a…
This article describes a new synthetic thickener/stabilizer technology that provides these attributes. Although there area variety of raw materials used to thicken personal care products, few are sufficiently versatile to offer effective thickening, gelling and suspending properties for a wide variety of applications.
Oct 28, 2011 | 03:22 PM CDT
The Required D-Value: Evaluating Product Preservation in Relation to Packaging and Consumer Use/Abuse
By: D.S. Orth, PhD, R.F. Barlow and L.A. Gregory, …
Cosmetic and pharmaceutical products are subject to microbial contamination and spoilage during use. In 1970, Halleck published the recommendations of the Preservation Subcommittee of the Toiletry Goods Association Microbiology Committee, which stated that preservation studies should consider product formulation, manufacturing conditions, packaging, product stability and continued effectiveness of the preservative system during the intended use by consumers.
Oct 28, 2011 | 01:45 PM CDT
Assessing the Safety of Parabens: Percutaneous Penetration and Risk Analysis
By: Elsa Jungman, Cécile Laugel and Arlette Baille…
In cosmetics, parabens are widely used due to their low cost and efficacy. In recent years, however, some reports have claimed that these materials exhibit estrogenic activity, which has led to attempts to replace them in formulations. This article reviews penetration studies of parabens spanning the past 20 years to determine whether they pose a risk to human health.