Evonik Corp. has introduced Vecollage Fortify GP, a revolutionary collagen polypeptide engineered to enhance skin health and functionality through an exosome-mediated, epigenetic-based mechanism. Designed to address aging skin and post-procedure care, this vegan, Type III human skin-identical collagen is said to deliver comprehensive benefits to both formulators and end users.
Vecollage Fortify GP Benefits and Functions
Vecollage Fortify GP (proposed INCI: Water (Aqua) (and) Glycerin (and) Propanediol (and) sh-Polypeptide-69) offers advanced biofunctionalities for targeted skin care innovation.
A dual anti-aging mechanism:
- Reducing extracellular matrix (ECM) degradation and
- Stimulating collagen production, fortifying the dermal-epidermal junction.
Exosome-mediated signaling :
- Harnessing microRNA signaling between keratinocytes and fibroblasts to reinforce structural integrity.
Skin-identical and sustainable:
- A 100% recombinant Type III collagen with a lower molecular weight than animal-derived collagen for improved absorption and compatibility, and
- Vegan and produced via a biofermentation process for ethical and eco-friendly formulations.
Clinically proven efficacy:
- Enhances skin elasticity, firmness and dermal density at concentrations as low as 0.3%.
Thus, Vecollage Fortify GP supports dermocosmetic formulations for pre- and post-medical procedures, anti-aging regimens and biomimetic skin care applications.
Proven Efficacy Through Rigorous Testing
The functionality and safety of Vecollage Fortify GP have been validated through a series of in vitro, ex vivo and in vivo studies.
- Gene expression (SimDerma Model): Demonstrated significant upregulation in ECM components, including collagen Types I and III.
- Protein expression (in vitro): Verified increased biosynthesis of procollagen Type I.
- Ex vivo models: Revealed strengthened dermal-epidermal junction and enhanced ECM renewal.
- Clinical studies (in vivo): Delivered measurable improvements in skin elasticity, firmness, and post-procedure recovery.
Per the company, these robust findings underscore its efficacy in enhancing collagen integrity, optimizing dermal structure and promoting renewal of the extracellular matrix.
Formulating Considerations
Vecollage Fortify GP is available as a preservative-free liquid (active matter ~2%) that per the company, is highly scalable due to its biofermentation production process. It offers excellent batch reproducibility and a recommended usage concentration of 0.3–2.5%.
Ideal for applications in anti-aging formulations, natural skin care and post-procedure solutions, VEcollage Fortify GP is designed to allow formulators to create high-performance, ethical products tailored to modern consumer demands.
With its precision-engineered collagen and sustainability-focused production, Vecollage Fortify GP is positioned as a disruptive solution for next-generation skin care innovation.
