PrimalHyal™ 50 Life, the virtuous revolution for Hyaluronic Acid

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Since its beginnings, Givaudan Active Beauty has been committed to creating active cosmetic ingredients with respect for nature. Elevated through ecological processes, iconic molecules are re-designed and transformed to better suit a science-led, nature-conscious future.

For the first time in the beauty industry, Givaudan Active Beauty has achieved a ground-breaking leap in the sustainability of Hyaluronic Acid production with its creation of PrimalHyal™ 50 Life: the most sustainable low molecular weight Hyaluronic Acid within Givaudan’s portfolio.*

Years of research have culminated in PrimalHyal™ 50 Life, a cornerstone in the sustainable development of the Hyaluronic Acid molecule. Leveraging strain engineering and precision fermentation, Givaudan Active Beauty production methods have been revolutionized to become more environmentally friendly, achieving an outstanding -91% reduction in environmental impact.*

Thanks to this sustainable breakthrough in its process, PrimalHyal™ 50 Life comprises significant improvements across various environmental parameters, as demonstrated by a Life Cycle Analysis,* boasting:

  • 92% greenhouse gas emissions;*
  • 95% acidification and eutrophication of water;*
  • 90% non-renewable energy usage;*
  • 75% water consumption.*

 PrimalHyal™ 50 Life bestows a multitude of potent skin care benefits, including:

  • Deep skin penetration, up to 120 µm;
  • Stimulation of tight junctions, preventing TEWL;
  • Boosted skin hydration for up to 72 hours post-application;
  • Reduction of skin roughness by -66% in 1 month;
  • Perceivable benefits in terms of skin texture, firmness and hydration, as noted by volunteers.

Romain Reynaud, research and development director commented: "Thanks to the outstanding work of our scientists in strain engineering, we have totally reinvented the production method for low molecular weight HA. By directly obtaining the molecular weight of interest during the fermentation stage, we have drastically reduced our global footprint. This is a breakthrough achievement for the beauty industry as a whole."

To learn more about this new ingredient, we invite you to connect to uxbeauty.givaudan.com, Givaudan Active Beauty’s digital platform dedicated to cosmetic ingredients.

*based on cradle-to-gate LCA carried out by an external firm in 2023 using specific Givaudan data. It follows the principles of the ISO 14 040 and 14 044 standards and the Environmental Footprint calculation method. Scope of analysis: A reference process route / Pathway with process optimisation


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