Recent in In vitro (page 9 of 11)
Apr 30, 2007 | Robert Holtz, BioInnovation Laboratories
Several interesting and promising approaches to in vitro skin sensitization testing are in development. Perhaps it will not be long before they are deemed valid and reliable alternatives to animal testing.
Mar 2, 2007 | Hongbo Zhai, MD, and Howard I. Maibach, MD, University of California at San Francisco School of Medicine
Described here was an in vivo model to determine antioxidative capacity of a topical skin care emulsion versus the emulsion’s vehicle on human skin that was exposed to UVR. Results suggest the test emulsion and its vehicle control inhibited the induction of erythema and reduced inflammation caused by the UV exposure.
Feb 1, 2007 | Robert Holtz, BioInnovation Laboratories
The methods described in this article highlight some of the markers that can be used to assess the UV protective effects of a test material. All of these markers represent either an index of UV-induced damage to the cell or the cell’s response to the damage.
Jan 2, 2007
Fluid Imaging Technologies has launched a particle analysis instrument that permits 23 measurement parameters.
Dec 1, 2006 | G. Guglielmini, Sinerga SpA
This article describes two sophisticated techniques to measure the diameter of emulsion droplets on the nanometer scale and uses those techniques to test a new emulsifying agent capable of spontaneously creating emulsions with droplet sizes smaller than 300 nm.
Sep 25, 2006
Ciba Specialty Chemicals has submitted a master file to the US Food and Drug Association (FDA) for its new antimicrobial test method...
Aug 31, 2006 | Janusz Jachowicz, ISP; Jo Smewing, Stable Micro Systems Ltd.
Texture analysis provides quantitative information about a material’s response when deformed by a controlled force. When texture analysis is applied to hair treated with various conditioners and styling fixatives, the results can help substantiate claims made about the effectiveness of these hair care products.
Aug 24, 2006
Celsis International introduces the next generation in bioluminescence technology that screens for microbial contamination of personal care products.
Aug 14, 2006
Beginning fall 2006, BioScreen will begin offering Asian subject panels.
Apr 17, 2006 | Bruce A. Buchholz and Howard I. Maibach
Quantification of percutaneous penetration and metabolism of skin care ingredients has seemed daunting; however, new technology provides a ready solution for the problematic arena. Accelerator mass spectrometry (AMS) is a new analytical method that measures a biological response better than the existing technique.
A Dermatological View: Using Photochemiluminescence to Quantify the Antioxidative Capacity of Topicals
Jan 2, 2006 | H Zhai, MD, and HI Maibach, MD, University of California School of Medicine
Exposure to ultraviolet radiation (UVR), air pollutants, chemical oxidants and aerobic microorganisms may damage the skin. In particular, reactive oxygen species (ROS) are considered a likely contributor to skin aging, cancer and certain skin disorders.
Dec 23, 2005 | Hongbo Zhai, MD, and Howard I. Maibach, MD, University of California at San Francisco School of Medicine
Pruritus or itching is an unpleasant sensation that provokes a desire to scratch. Many factors such as chemical, mechanical, thermal and electrical stimuli can elicit the itch sensation. Mediators of itch presumably directly act on nerve fibers or lead to a nerve stimulation cascade whose final common pathway is interpreted in the central nervous system as itching. Putative receptors for itching are C-fibers with exceptionally low conduction velocities and insensitivity to mechanical stimuli. Histamine, the proto-typical chemical mediator of itch, which is released during mast cell degranulation and mediates its effects in the skin via H1 receptor, is the best-known experimental pruritogen.