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New in In vitro (page 9 of 15)
Feb 27, 2009 | 10:56 AM CST
By: Nava Dayan, PhD, Lipo Chemicals Inc.
Ex vivo skin absorption studies measure the penetration and permeation of a compound to assess its safety, and can assist the formulator in increasing product efficacy and reducing toxicity. This review analyzes the currently available guidelines published by four major regulatory organizations to clarify important milestones in study design, data analysis and interpretation.
Feb 23, 2009 | 02:31 PM CST
By: Johann W. Wiechers, PhD, JW Solutions
In this column, the author investigates the source of the placebo effect. In addition, he asks the question: Must cosmetics testing always incorporate tests against a placebo?
Jan 30, 2009 | 02:28 PM CST
By: Hongbo Zhai, MD, and Howard I. Maibach, MD, Un…
The current preliminary study compared the sensitivity and correlation of open chamber device and closed chamber device on a tape stripping human model. The amount of SC removed by tape stripping was also quantified with a protein assay method.
Jan 29, 2009 | 04:31 PM CST
This first effort is focused on the key performance attributes of shampoos, 2-in-1 shampoo and conditioners and shampoo/conditioner systems.
Dec 19, 2008 | 04:39 PM CST
The European Centre for the Validation of Alternative Methods' (ECVAM) Scientific Advisory Committee (ESAC) endorsed the scientific validity of two in vitro skin irritation tests at its 29th meeting.
Oct 30, 2008 | 04:54 PM CDT
By: Lawrence A. Hough, Denis Bendejacq and Tobias …
In the present article, the authors characterize a multilamellar vesicle (MLV) system used in personal care and verify its structure via X-ray scattering, rheology and fluorescence microscopy. This enabled the study of MLV formation to investigate bulk rheology characteristics. The results are presented here as application-relevant properties.
Oct 01, 2008 | 04:55 PM CDT
By: Robert Holtz, BioInnovation Laboratories
Many markers can be used to indicate epidermal stress. Therefore, it becomes clear that the skin is also a sensitive target to ozone exposure and one that could greatly benefit from cosmetic or personal care materials designed to protect against ozone.
Sep 24, 2008 | 10:02 AM CDT
Lonza announces the availability of primary Clonetics Adult Normal Human Epidermal Melanocytes.
Aug 29, 2008 | 04:50 PM CDT
By: Theresa Callaghan, PhD
It remains the responsibility of the manufacturer to substantiate the safety of both ingredients and finished cosmetic products prior to their being marketed.
Aug 29, 2008 | 04:22 PM CDT
By: Miranda Farage, PhD, Procter & Gamble and Howa…
Manufacturers of topical products perform rigorous testing to assure that their products are safe for consumers. Of particular interest is determining whether products will irritate the skin of the approximately 50% of consumers surveyed who consider themselves to have “sensitive” skin.