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In vitro
Excerpt Only
Antiaging in a Different Light: Assessing How Chromophores Color Perception
By: Philippe Mondon, Nada André, Emmanuel Doridot, Olga Gracioso and Karl Lintner, PhD, Sederma SAS
Posted: July 30, 2010, from the August 2010 issue of Cosmetics & Toiletries.
Purchase This Article
- From Cosmetics & Toiletries
- August 2010 issue, pg 26
- 7 pages
Article Keywords:
- chromophores
- collagen
- heterogeneity
- darutoside
- oridonin
- spectrophotometric intracutaneous analysis
Available Formats:
- Adobe PDF for download
- Printed copies mailed to you
From $9 an article
In general, beautiful skin is perceived as being blemish-free, a characteristic often associated with youthful skin. During aging, a progressive decline in functions in the skin gives rise to, among other things, the emergence of visible heterogeneity of the skin including redness, blemishes, blotches, wrinkles and rough spots that are more readily noticeable. Pro-inflammatory messengers induce local redness and greater sensitivity of the blood vessels to environmental or behavioral stress. Similarly, oxidative stress and pro-inflammatory messengers stimulate pigmentation. Also, the dendricity of melanocytes increases while the phagocyte activity of keratinocytes on melanosomes is augmented. This results in the localized appearance of lentigines and hyperpigmentation.1
Lab Practical: Employing the SR Complex
- The SR active comples is soluble in water.
- It is easily incorporated into emulsions between 25°C and 80°C.
- The material is compatible with most cosmetic ingredients, including ethanol.
- The blend is preservative-free.
This is only an excerpt of the full article that appeared in Cosmetics & Toiletries, but you can purchase the full-text version.

