Testing for Dioxin and Furan Contamination in Triclosan

May 6, 2003 | Contact Author | By: J. Menoutis and A. I. Parisi, Quantex Laboratories Inc.
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Keywords: triclosan | antimicrobials | 2 | 3 | 7 | 8-tetrachlororodibenzo-p-dioxin | 2 | 3 | 7 | 8-tetrachlorodibenzofuran | dioxin | furans

Abstract: Each batch of triclosan should be analyzed for trace amounts of 2 3 7 8-tetrachlorodibenzo-p-dioxin and 2 3 7 8-tetrachlorodibenzofuran, which can form as unwanted manufacturing by-products, as shown in triclosan from six commercial Asian sources.

Triclosan is a broad-specrum antibacterial/antimicrobial agent first introduced commercially more than 30 years ago. Because of its bacteriostatic properties against a wide range of both Gram-negative and Gram-positive bacteria, it has found popular and increased use in various personal care products such as toothpaste, deodorants, handsoaps, bodywashes, dishwashing liquids and cosmetics. It has also found uses as an additive for plastics and polymers and as a textile treatment that reportedly gives these materials bacteriostatic properties.