Recent in Testing (page 1 of 32)

Phthalates Study Raises More Concerns, ‘But Who Cares?’

It’s been a while since a cosmetic ingredient was slandered. To ensure we’re not letting you down, here’s a report on new study examining the negative impact of phthalates.

CIR Gives Certain Keratin, Polymers and More the OK for Safety

The Cosmetic Ingredient Review Expert Panel has made a safety determination on a number of chamomile, polymer, keratin and sulfate ingredients. Some are safe for use at certain levels while two HDI polymers still have insufficient data.

In vivo Delivery Confirmation: Measuring the Deposition of Salicylic Acid from Anti-acne Face Wash

Measuring the delivery of active ingredients is an important part of the product development process, and particularly desirable are non-invasive, in vivo methods. This work describes the use of fluorescence excitation emission matrices in vivo to measure the deposition of salicylic acid from anti-acne face wash products.

Wet Skin Factor for Sunscreens: An In vitro Method, Part II

Sunscreens designed for application to wet skin are popular in part due to convenience, skipping the drying step completely. In relation, these authors propose a new in vitro test to compare the wet skin factor of sun care products. Here, 20 products were tested and compared according to several conditions in order to define the best parameters for the method.

Wet Skin Factor for Sunscreens: An In vitro Method, Part I

Sunscreens designed for application to wet skin are popular in part due to convenience, skipping the drying step completely. In relation, these authors propose a new in vitro test to compare the wet skin factor of sun care products. Here, 20 products were tested and compared according to several conditions in order to define the best parameters for the method.

Heat Protection Getting Warmer: Specialty Silicones for Hair

The present study examines the ability of silicones to protect hair during heat styling, compared with other industry benchmarks and untreated hair. Also discussed are the mechanisms through which different silicones contribute heat protection in hair care products such as leave-in conditioners, serums and other product forms.

Nonreactive Paths to Internal Changes: Modifying Hair’s Structure from the Inside, Part 2

Scientific evidence suggests that nonreactive compounds have the ability to modify hair’s structure, providing formulators additional ways to craft products and worry less about hair damage.

Dry Heat Transdermal System Launched to Benefit Testing

To help test creams, lotions, ointments and patches, Logan Instruments Corp. launched DHC-6T, a dry heat transdermal diffusion cell system. With interchangeable glass volumes, this system helps keep Franz cells from breaking, among other beneficial features.

VIDEO: P&G Scientists on Claims Substantiation in Anti-dandruff Care

Head & Shoulders recruits an army to prove the benefits its brand delivers to consumers. Hear more in this video.

'Zapping' Sensitive Skin: Capsaicin Tests Show Embelia concinna Comforts Irritation

In previous work, a flavonoid-titrated active ingredient based on Embelia concinna was shown in vitro to calm and soothe sensory neurons stimulated with capsaicin. Here, those results are confirmed in vivo using a capsaicin stinging test with human volunteers.

Can New Approaches Pave the Way for Better Toxicology?

The ECHA is hosting a topical scientific workshop April 19-20 that examines new approaches to animal testing alternatives and chemical safety assessments.

SPF Tests Reveal No Ideal In vitro Substrate Exists

In vitro SPF measurements are challenged by reproducibility, repeatability and correlation with in vivo values. Here, the authors assess sunscreen adhesion to the test substrate support, since poor adhesion produces bad results. Surface substrates are characterized by functional group, charge, wettability and surface morphology. Eight w/o and o/w emulsions also are tested. Results indicate an ideal in vitro test substrate does not exist.

Can't find what you're looking for? Try searching, or looking through past issues.