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Type: Article

Section: Testing > Efficacy

After 14 days, M. cochinchinensis extract improved stinging, irritation, itch and discomfort by 67%, 100%, 91% and 100%, respectively.

Holistically Derailing the Sensitive Scalp ‘Rollercoaster’

A Maclura cochinchinensis extract was developed to provide holistic relief for sensitive scalps by derailing multiple interconnected aspects of this “rollercoaster” condition. The active’s efficacy was tested in vitro and in vivo as described here.

To provide a natural solution for sensitive skin, a hyperbranched dextrin was developed and tested for soothing and protective effects. The absence of adverse effects on the microbiome also was assessed by a third party, with promising results.

Hyperbranched Dextrin for Soothing, Microbiome-friendly Skin Care

To provide a natural solution for sensitive skin, a hyperbranched dextrin was developed and tested for soothing and protective effects. The absence of adverse effects on the microbiome also was assessed by a third party, with promising results.

Transdermal microneedle patches enable active ingredients to bypass the slow diffusional process across the stratum corneum’s barrier to reach directly into the deeper skin layers.

How Dissolving HA Microneedles Change Before/After Application

Dissolvable microneedles have gained popularity to overcome the skin barrier and deliver actives. Here, SEM was used to evaluate changes that occur to microneedles upon application. The results could provide claims and regulatory classification insights.

The present study examined the effects of commercially available jojoba esters in liquid, natural jojoba-like form in three studies measuring irritation mitigation, skin hydration and soothing properties.

Jojoba Oil Esters Ease Inflammation, Sensitivity and Water Loss from Skin and the Environment

Water scarcity has become a major concern and jojoba is known to flourish under controlled low water conditions. As such, jojoba wax esters were explored for skin care to reduce inflammation and sensitivity and to provide hydration over a 24-hr period.

In evaluating how different solvents may affect the rheology of personal care formulas, it is helpful to consider that different formulation types have distinct relationships between viscosity and elasticity depending on the factors generating their elastic properties.

How Natural Butylene Glycol Advances Market and Rheology Dynamics

Demand for sustainable ingredients in cosmetics and personal care is well-known. Here, a sustainable natural butylene glycol is described to advance this trend and its effects on viscosity and elasticity are assessed in five test formulas.

Like other markets, efficacy testing, including for cosmetics, is projected to have a substantial increase in revenue by 2027, largely due to pharmaceuticals and biotechnology making constant advancements in relation to public views and the pandemic.

Efficacy Testing Market Worth $423 Million by 2027

Like other markets, efficacy testing, including for cosmetics, is projected to substantially increase in revenue by 2027, largely due to pharmaceuticals and biotechnology making constant advancements in relation to public views and the pandemic.

To prevent and repair UV-induced skin damage, a sustainable ingredient was developed from Sargassum vulgare, a brown seaweed that naturally evolved phlorotannins to defend against UV damage. The algae was fermented using a proprietary yeast to enrich this bioactive content; the resulting ingredient was tested as described here for skin benefits.

Brown Seaweed Ferment Propagates UV Damage Protection for Skin

To prevent and repair UV-induced skin damage, a sustainable ingredient was developed from Sargassum vulgare, a brown seaweed that naturally evolved phlorotannins to defend against UV damage.

For multifunctional products such as moisturizing hand sanitizers, the sanitizer claim requires a significant reduction (2-3 log) of a microorganism population while the moisturizer claim requires data showing an increase in skin moisture.

Testing the Safety and Efficacy of Multifunctional Personal Care Products, A Primer

Multifunctional products may offer solutions to consumer challenges but as the needs of consumers grow more complex, so do their safety and efficacy testing. This article provides a primer on these considerations.

Eurofins Ct2203 Lead

Reduction of skin stress by CBD products: Aiming high above the competition

The use of cannabinoid products is growing in popularity. Formulate with cannabinoids confidently with effective technology development strategy from Eurofins – download a free brochure on CBD testing for safety and compliance.

Silicones are widely used as binders in pressed powders but growing consumer skepticism has prompted the use of alternatives. The aim of this study was to assess the efficacy of three plant-derived natural binders in obtaining optimal pressed powders, using dimethicone as a standard.

‘Pressed’ for Powders: Replacing Dimethicone with Plant-derived Alternatives*

The aim of this study was to assess the efficacy of three plant-derived natural binders in obtaining optimal pressed powders, using dimethicone as a standard.

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Stress and Psoriasis: How TCM Herbs Can 'Cool' Inflamed Skin

This study explores how TCM can be leveraged in skin products to holistically improve conditions such as psoriasis. In particular, properties of honeysuckle, Rehmannia glutinosa and rhubarb are described and tested here in vivo.

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Colorfast Effects: Reflectance to Assess Lip Gloss Water Resistance, A Proposal

This approach is tested for its ability to distinguish waterproof and non-waterproof products, and compared with in vivo results. Proposed here is in vitro method to measure the waterproof properties of lip gloss based on UV/Vis spectrophotometer reflectance values.

genemarkers_ct2109_lead

Validate the efficacy of actives, raw materials & products in preventing/repairing skin damage from environmental pollution

Learn more about The Environmental Stress Panel – an innovative gene expression panel developed by Genemarkers, the leader in applying state-of-the-art genomics technologies to personal care product development.

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Securing Skin: Polysaccharides Deliver Anti-pollution Protection

The present work tests the antioxidant and anti-inflammatory effects of cosmetic polysaccharides for anti-pollution benefits. Air pollution is rising and can negatively impact skin. As such, anti-pollution cosmetics are trending.

Johann W. Wiechers, Ph.D.

Words from Wiechers: All That is Good is Bad

We need to keep in mind that we may be able to maintain an appearance of youth and even measure the difference in a chemical marker in two people; but we need to avoid the Dorian Gray effect.

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Fighting AGEs Formation: Upcycled Artichoke Inhibits Glycation, Increases Skin Firmness

Upcycling organic waste into cosmetics has been of interest for the growing sustainability trend—and artichoke, in particular, demonstrates anti-aging activities. Described herein is the development of an upcycled artichoke byproduct, which was tested for effects on skin glycation and elasticity.

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Propanediol Caprylate: Shifting the Microbiome, Sebum Levels and Classic Approach to Dandruff

Propanediol caprylate was previously shown to deactivate Malassezia for dandruff control. In parallel, its effects to shift the balance of Cutibacterium and Staphylococcus in the scalp microbiome, and reduce dandruff and sebum are explored here.

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Industry Insight: Testing the Most Efficient Color Shampoo/Conditioner Duos

In this "Industry Insight," Sabina Wizemann, senior chemist of the Health, Beauty and Environmental Sciences Lab at the Good Housekeeping Institute has evaluated shampoo and conditioner pairs to identify the best performers for hair dye retention. In a recent interview, she explained how she tests these products, analyzes their efficacy and claims, and which duos exemplified the highest efficacy, compared with other products.

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