Patent Picks—Gels for Anti-acne and Wrinkle-blurring, Oridonin for Slimming and More

By: Rachel L. Grabenhofer

Posted: October 27, 2010

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Described here are dermatological/cosmetic gel compositions suited for preventing or treating cell differentiation and/or proliferation and/or keratinization disorders, including preventing or treating common acne. The disclosed compositions comprise at least one retinoid, dispersed benzoyl peroxide, and at least one pH-independent gelling agent; all of which are formulated into a physiologically acceptable medium.

Oleaginous pharmaceutical and cosmetic foam
US Patent 7820145
Publication date: Oct. 26, 2010
Assignee: Foamix Ltd.

The invention relates to stable oleaginous cosmetic or therapeutic foam compositions containing certain active agents and having unique therapeutic properties as well as methods of treatment using such compositions. The foamable composition includes at least one solvent selected from a hydrophobic solvent, a silicone oil, an emollient, a cosolvent, and mixtures thereof; wherein the solvent is present at approximately 70% to 96.5% w/w of the total composition, the nonionic surface-active agent at approximately 0.1% to < 10% w/w of the total composition; and at least one gelling agent at approximately 0.1% to 5% w/w of the total composition. In addition, a therapeutically effective amount of at least one active agent and at least one liquefied or compressed gas propellant at approximately 3% to 25% w/w of the total composition is included.

SOD/catalase mimetics for the treatment of skin damage
WO/2010/120875
Publication date: Oct. 21, 2010
Assignee: Eukarion Inc. and Bernard Malfroy-Camine

Diclosed in this patent are methods and an apparatus for diagnosing and treating oxidative skin damage in a subject. The therapeutic method can comprise: a) diagnosing a level of oxidative skin damage in the stratum corneum of a subject; and b) recommending a therapeutic regimen for the treatment of oxidative skin damage in a subject, wherein said recommendation comprises a pharmaceutical formulation including one or more specific synthetic SOD/catalase mimetics sufficient to treat the level of damage diagnosed. The diagnostic method can further include obtaining a sample from the stratum corneum of a subject; measuring the level of at least one oxidized substance in the sample; and comparing a detected level of the oxidized substance with a standard, whereby an elevated level of the oxidized substance is indicative of skin damage.