Recent in Chemistry (page 6 of 9)

Caprylyl Glycol/Phenethyl Alcohol Blend for Alternative Preservation of Cosmetics

In recent years, the safety of traditional preservatives has been called into question. Therefore, there is a need for alternatives that are effective, safe and sustainable—and that are non-controversial. In response, the present work investigates a mixture of caprylyl glycol and phenethyl alcohol, which is shown to provide antimicrobial activity in various skin and hair care formulations.

Formulating Focus: The Influence of Emollients on Skin Penetration

This column will discuss ways in which ingredients can positively affect the partition coefficient of the active between the formula and the skin. By carefully selecting the emollients used in a formulation, formulators can increase the delivery and clinical efficacy of a formulation without increasing the level of the active ingredient.

Technically Speaking: From Enzymes to Fragrance Ingredient Testing: A Literature Overview

The following column discusses the latest technological advancements in the fields of hair care, skin care, oral care, sunscreen, color cosmetics and more.

Heralding the Future, Appreciating the Past

In this month’s issue, we honor Maison “Ed” G. deNavarre. Not only did this legend inspire the creation of the IFSCC and pull together an encyclopedia of knowledge that still resonates, he drove emulsion technology to new heights.

Improving the Solubility of Benzoyl Peroxide: A Review

In this review, the authors examine studies relating to the solubility of BPO. The clinical trials discussed show that compared with suspended BPO, BPO solubilized by dimethyl isosorbide reduced P. acnes and decreased both inflammatory lesions/irritation and the emergence of antibiotic-resistant P. acnes strains. This reveals the importance of solubilizing BPO for improved efficacy and safety.

Developments in Ceramide Identification, Synthesis, Function and Nomenclature

Advances have been made in recent years to better understand ceramides, as the authors describe here. However, since not all ceramides have the same structure, the nomenclature in the literature and on product labels needs clarification. The Personal Care Products Council recently agreed upon new nomenclature based on four molecular structures, which the authors also discuss.

Formulating at pH 4-5: How Lower pH Benefits the Skin and Formulations

Most skin products are formulated around pH 6 but the latest research in skin biology suggests the skin is significantly more acidic—around 4.7. Here, the author shows how formulating for this natural pH can enhance the skin penetration of actives, reduce the amount of preservatives required, and increase chemical stability.

Profile of Mica

Mica is an inorganic material found in a wide variety of cosmetic and personal care products. Its use has been reported in more than 7,100 products, making it one of the most important mineral ingredients used in cosmetics.

Amphiphilic Silicones to Extract Botanical Actives

Silicone-based compounds enable chemists to extract the desired fractions of materials from plants as well as impart cosmetic aesthetics. Here the authors discuss how to extract actives using amphiphilic silicones that have different partition coefficients, which are obtained by altering the ratio of oil-, water- and fluoro-soluble groups on the silicone molecule.

Small, Smaller and Nano Materials: An Invisible Benefit

Although nanomaterials have been used in cosmetics for some time, consumers believe they may constitute a health risk due to their possible penetration into the skin. The present article evaluates the benefits as well as the skin penetration of nanoparticles used in cosmetics.

Ingredient Profile—Sorbic Acid/Potassium Sorbate

SorbH and KSorb have become increasingly popular options for cosmetic preservatives due to their worldwide status as Generally Recognized As Safe (GRAS) food ingredients and their long and successful use history.

Comparatively Speaking: Arrow Symbols in Organic Chemistry*

Tony O’Lenick asks organic chemistry expert and founder of website Master Organic Chemistry James Ashenhurst, PhD, to explain the eight types of arrow symbols.

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