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CIR Reaches Verdicts on Butyl Myristate, HC Red No. 3 and More
Posted: June 17, 2008
page 15 of 16
Interested parties with data relevant to the safety assessment of these additional cosmetic ingredients are encouraged to provide such data by Aug. 3, 2008. In considering the addition of other chemicals, the safety of which may be addressed by the original safety assessment, the CIR Expert Panel has indicated that the phrase “chemically related” could include inorganic salts and simple esters.
The Panel also stated that it would consider the types of products in which any additional cosmetic ingredients are used and the concentrations at which they are used.
6. Next CIR Expert Panel meeting
The next CIR Expert Panel meeting will be Sept. 22-23, 2008, at The Madison, A Loews Hotel, 1177 Fifteenth St. NW, Washington, DC 20005, USA; Tel: 1-202-862-1600.
7. 2009 Meeting Schedule
The meeting schedule for 2009 has been set. In 2009, the CIR Expert Panel will meet: Mar. 23-24; June 29-30; Sept. 24-25; and Dec. 7-8.
1. This safety assessment was reopened in December 2007 because of concerns about the limited genotoxicity data and the absence of carcinogenicity data for toluene-3,4-diamine. At that time, the expert panel considers that the available data are insufficient to support the safety of this ingredient. Data needed for toluene-3,4-diamine included mammalian genotoxicity data. If positive, a two-year dermal carcinogenicity study using NTP methods may be needed. Concentration of use and dermal penetration data also would be useful. Any data received will be included in the SLR.