Chitin Nanofibrils for Improved Photoprotection

Sep 1, 2009 | Contact Author | By: Pierfrancesco Morganti, University of Naples II, China Medical University and Mavi Sud s.r.l.; Giuseppe Fabrizi, Eleonora Ruocco, Paola Del Ciotto, Paolo Palombo, Marco Palombo and Antonio Cardillo
Your message has been sent.
(click to close)
Contact the Author
Save
This item has been saved to your library.
View My Library
(click to close)
Save to My Library
Title: Chitin Nanofibrils for Improved Photoprotection
Photoprotectionx sunscreen boosterx chitin nanofibrilsx protection factor of UVA (PFA)x
  • Article
  • Media
  • Keywords/Abstract

Keywords: Photoprotection | sunscreen booster | chitin nanofibrils | protection factor of UVA (PFA)

Abstract: Chitin nanofibrils (CN) are capable of interacting with cosmetic actives by binding to the stratum corneum, thus influencing their thermodynamic activity. Here, the authors test various sunscreen samples and determine that the addition of CN provides an interesting boost to the photoprotective activity of sunscreens.

Excerpt Only This is a shortened version or summary of the article you requested. To view the complete article, please log in or create an account. Registration is Free!

Consumers are educated about the damaging effects of excessive UV radiation on the health and appearance of skin. This has driven the medical community and consumers to demand increasing levels of protection from sun care products, in addition to improved emollient and anti-inflammatory properties.1–4

UVA and UVB radiation causes the direct absorption of photons by DNA and subsequent structural changes, in addition to the generation of reactive oxygen species (ROS), resulting in lipid peroxidation. Moreover, UV radiation impairs the human immune response by increasing the activity of suppressor T-cells.5 The effects of UVA and UVB radiation have created the need for sunscreen products. For example, several studies show that both UVA and UVB increase the production of matrix metalloproteases (MMPs) four- to five-fold, resulting in the remodelling and degradation of the extracellular matrix (ECM).6–9

Excerpt Only This is a shortened version or summary of the article you requested. To view the complete article, please log in or create an account. Registration is Free!

 

Close

Table 1. Test formulations used for group A

 Table 1. Test formulations used for group A

Table 2. Test formulations used for group B

 Table 2. Test formulations used for group B

Table 3. Proportionate UVA protection values at increasing SPF levels

 Table 3. Proportionate UVA protection values at increasing SPF levels

Morganti Improved Photoprotection footnotes

 aChroma Meter CR-300 is a device manufactured by Minolta Co., Tokyo.

b Schott Color Glass Filters WG-320 and UG-11 are products of Schott AG, Mainz, Germany.

c The R-B meter is a device manufactured for the researchers by the University La Sapienza, Rome.

dTL 10R and TL 09R are lamps manufactured by Philips Lighting Company, Amsterdam, Netherlands.

eSchott WG-335 is a colored glass filter produced by Schott AG, Mainz, Germany.

fGraphPad Prism 4 is manufactured by GraphPad Software Inc., La Jolla, Calif., USA.

Next image >

 
 

Close

It's Free...

Register or Log in to get full access to this content

Registration includes:

  • Access to all premium content
  • One click ingredient sample requests
  • Save articles in the My Library tool

Create an Account or Log In