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Metabolism and Modulation of Hyaluronan Levels in Skin

By: Birgit A. Neudecker, Antonei Benjamin Csoka, Susan Stain Nawy, Howard Maibach and Robert Stern, University of California; and Kazuhiro Mio, Lion Corp.
Posted: May 6, 2003

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This is the last in a series of articles that review the literature on hyaluronan, which also sometimes goes by the name hyaluronic acid. In this article, we will use HA as an abbreviation for either term.

Skin retains a large amound of water, but experiences losses of that moisture due to the normal process of aging and external trauma to which the skin is subjected. One key molecule involved in skin moisture is HA, a natural moisturizer of the skin.

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