DNA: Hard Evidence of Cosmeceutical Claims

May 1, 2009 | Contact Author | By: Katie Schaefer, Cosmetics & Toiletries magazine
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Title: DNA: Hard Evidence of Cosmeceutical Claims
genex RNAx DNAx Real Time PCRx
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Keywords: gene | RNA | DNA | Real Time PCR

Abstract: To support finished product or raw material claims these two in vitro methods—the Affymetrix microarray and the Taqman Real Time Polymerase Chain Reaction (PCR)—measure the up-regulation or down-regulation of genes.

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Products have evolved to serve multiple functions, treading the line between industries and stirring the emergence of such terms as cosmeceutical and nutricosmetic. While some dismiss this as mere marketing, the associated claims cannot be ignored; and as an overabundance of claims becomes more indecipherable for the consumer, regulatory bodies such as the Better Business Bureau and the US Food and Drug Administration are cracking down on manufacturers for the messages they convey, requiring they be backed by solid science.

To support finished product or raw material claims, Anna Langerveld, PhD, of Genemarkers LLC, has developed two in vitro methods—the Affymetrix microarray and the Taqman Real Time Polymerase Chain Reaction (PCR)—to measure the up-regulation or down-regulation of genes.

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Human Genome Project (HGP)

Completed in April 2003, the HGP provided researchers with the ability to read the complete genetic blueprint of human beings. Arrays of DNA can be spatially arranged onto a gene chip to accomplish thousands of genetic tests in parallel, dramatically accelerating test results.

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