Recent in Testing (page 22 of 32)

Webinar Focused on Cell-based Assays

BD Biosciences is hosting a webinar dedicated to cell-based assays. Elizabeth Abraham, PhD, a research scientist at BD Biosciences, will discuss the applications for the company's BD PureCoat surfaces.

In the Land of the Blind: Applying a Single-blind Study to Finished Products

Following positive feedback from a previous column on the placebo effect, Wiechers readdresses clinical study design in relation to cosmetic claim substantiation—this time discussing when to perform double-blind studies and when to perform single-blind studies.

Genetic Test for Alopecia Approved in Europe

The HairDX Genetic Test for Hair Loss, a genetic baldness test manufactured by HairDX LLC, is now available as a CE Marked product under the European In Vitro Diagnostic Directive.

Falling Ball Viscometer for Newtonian Fluid Measurement

Brookfield Engineering celebrates its 75th anniversary with the introduction of the Falling Ball Viscometer, an instrument to assess the dynamic viscosity of transparent Newtonian fluids.

Characterizing Roughness: A New Substrate to Measure SPF

Here, the authors describe a variable that affects the results of SPF testing in vitro—the roughness parameter—and investigate this variable using standard and molded poly(methyl methacrylate) (PMMA) substrates. They conclude that use of a molded substrate, along with the described control chart, improves the reproducibility of in vitro SPF test results.

ECVAM Calls for Testing Experts

The European Centre for the Validation of Alternative Methods (ECVAM) is renewing its scientific advisory structure and is calling for life sciences experts interested in joining its ESAC or EEP groups.

Virtually Real

This edition of C&T magazine takes a closer look at alternatives to animal testing with Oborska’s review of existing and pending methods. In addition, the author discusses the complexity of the process to validate alternative test methods.

Alternatives to Animal Testing: A Review of Trends and Perspectives

Alternative test methods have the potential to reduce animal testing; however, the extent to which in vitro methods can be replaced is questionable. This article summarizes validated alternatives to test the safety of cosmetic ingredients. It also illustrates how great a challenge it is to devise a proper alternative method.

Cutest Offers UVA Sunscreen Testing

Cutest Systems Ltd has installed a Labsphere UV-2000S sunscreen analyzer at the companies laboratories in Cardiff, Wales.

Evaluating Water Permeability and Occlusion in Wound Dressings and Topical Cosmetics

The present study uses an evaporimeter to measure the degree of water loss from in vitro skin samples covered by occlusive and semi-occlusive wound dressings to serve as a model for determining the effectiveness of occlusive cosmetic formulations. The purpose of this work was to develop a model for determining the effectiveness of occlusive cosmetic formulations.

DNA: Hard Evidence of Cosmeceutical Claims

To support finished product or raw material claims these two in vitro methods—the Affymetrix microarray and the Taqman Real Time Polymerase Chain Reaction (PCR)—measure the up-regulation or down-regulation of genes.

In vivo Quantification of Corneocyte Lipids by Image Analysis

In a new method described here by the authors, fluorescence emitted from samples and captured by image analysis is used to quantify the number of lipids present in the cornified cell envelope. This in vivo approach is fast and noninvasive and could be used to screen molecules for potential moisturizing and restructuring effects.

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