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Recent in Testing (page 22 of 32)
Aug 28, 2009
The European Centre for the Validation of Alternative Methods (ECVAM) is renewing its scientific advisory structure and is calling for life sciences experts interested in joining its ESAC or EEP groups.
Jul 30, 2009 | Rachel Chapman, Cosmetics & Toiletries magazine
This edition of C&T magazine takes a closer look at alternatives to animal testing with Oborska’s review of existing and pending methods. In addition, the author discusses the complexity of the process to validate alternative test methods.
Jul 30, 2009 | Anna Oborska, PhD, Polish Association of Cosmetics and Home Care Products Producers
Alternative test methods have the potential to reduce animal testing; however, the extent to which in vitro methods can be replaced is questionable. This article summarizes validated alternatives to test the safety of cosmetic ingredients. It also illustrates how great a challenge it is to devise a proper alternative method.
Jul 1, 2009
Cutest Systems Ltd has installed a Labsphere UV-2000S sunscreen analyzer at the companies laboratories in Cardiff, Wales.
Jun 30, 2009 | Hongbo Zhai, MD, and Howard I. Maibach, MD, University of California
The present study uses an evaporimeter to measure the degree of water loss from in vitro skin samples covered by occlusive and semi-occlusive wound dressings to serve as a model for determining the effectiveness of occlusive cosmetic formulations. The purpose of this work was to develop a model for determining the effectiveness of occlusive cosmetic formulations.
May 4, 2009 | Katie Schaefer, Cosmetics & Toiletries magazine
To support finished product or raw material claims these two in vitro methods—the Affymetrix microarray and the Taqman Real Time Polymerase Chain Reaction (PCR)—measure the up-regulation or down-regulation of genes.
May 4, 2009 | David Boudier, Nathalie Guichard, Josselin Breugnot, Maud Le Guillou and Brigitte Closs, Silab
In a new method described here by the authors, fluorescence emitted from samples and captured by image analysis is used to quantify the number of lipids present in the cornified cell envelope. This in vivo approach is fast and noninvasive and could be used to screen molecules for potential moisturizing and restructuring effects.
Apr 1, 2009 | Hongbo Zhai, MD, University of California; and Howard I. Maibach, MD, University of California School of Medicine
The present study utilized an in vitro model to compare the decontamination capacity of three model decontaminant solutions: tap water, isotonic saline and hypertonic saline. Human cadaver skin samples were dosed with radio-labeled [14C]-formaldehyde and the surface skin of each sample was washed after each exposure with one of the three model decontaminant solutions.
Feb 27, 2009 | Nava Dayan, PhD, Lipo Chemicals Inc.
Ex vivo skin absorption studies measure the penetration and permeation of a compound to assess its safety, and can assist the formulator in increasing product efficacy and reducing toxicity. This review analyzes the currently available guidelines published by four major regulatory organizations to clarify important milestones in study design, data analysis and interpretation.
Feb 27, 2009
Knight Scientific Ltd. offers a kit to manufacturers to measure the antioxidant capacity of their finished nutraceuticals and cosmetics to justify claims, produce technical documents, confirm batch uniformity and more.
Feb 23, 2009 | Johann W. Wiechers, PhD, JW Solutions
In this column, the author investigates the source of the placebo effect. In addition, he asks the question: Must cosmetics testing always incorporate tests against a placebo?
Jan 30, 2009 | Hongbo Zhai, MD, and Howard I. Maibach, MD, University of California School of Medicine
The current preliminary study compared the sensitivity and correlation of open chamber device and closed chamber device on a tape stripping human model. The amount of SC removed by tape stripping was also quantified with a protein assay method.
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Between The Covers Discover:
- Amino acid distribution and biochemistry
- Examination of strength and anti-breakage product claims
- Hair: growth cycle, heat protection, shine, and color intensity and retention
- Overview of shampoos and issues relating to surfactants
- Science of hair color including chemical reactions and formulations
- Ethnic differences in hair and absorption of materials
- Evaluate and quantify visual properties of hair
- Dandruff-Causes and biology of the condition
- Hair styling products and polymers
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Finally! This book offers practical approach to the formulation chemist’s day-to-day endeavors by: addressing the innumerable challenges facing the chemist both in design and at bench, such as formulating with/for specific properties; offering valuable “tips” to troubleshooting issues regarding ingredient selection and interaction, regulatory concerns that must be addressed early in development, and the extrapolation of preservative systems; exploring the advantages and limitations of raw materials; addressing scale-up and pilot production process and concerns; and much more.Order your copy today.