Patent Picks—Etyllinoleate, Dibenzoyl Peroxide, Pentane-1,5-Diol, Microcapsules and More for Treating Acne

By: Katie Anderson (Schaefer), Cosmetics & Toiletries magazine

Posted: July 12, 2011

page 5 of 5

This invention relates to skin pore tighteners each of which comprises, as an active ingredient, a compound represented by the following formula: R¹—OG, wherein R¹ represents an alkyl or alkenyl group with 8 to 32 carbon atoms and OG represents a residual group obtained by removing a hydrogen atom from a hydroxyl group of a polyhydric alcohol, monosaccharide or oligosaccharide, at least one hydroxyl group of which has been sulfated or phosphatized, or a salt thereof.

The skin elasticity improvers comprise, as an active ingredient, a glyceryl ether derivative represented by the following formula: wherein R¹ represents the same group as defined above, and X¹ and X² each independently represents a hydrogen atom, —SO₃OH or —PO(OH)₂ with the proviso that X¹ and X² are not hydrogen atoms at the same time, or a salt thereof.

Iodide salts of dimethylaminoethanol fatty acid esters with bacteriostatic, mycostatic, yeaststatic and/or microbicide activity for use in cleansing or purifying formulations
European Patent EP1892236
Publication Date: June 22, 2011
Assignee: Scharper S.p.A.

The applicant has now prepared new salts of dimethylaminoethanol fatty acid esters of general formula in which R is a C₆-C₁₆ linear or branched alkyl radical, X^- = l^-, and which, as well as being biocompatible, has bacteriostatic, mycostatic, yeaststatic and/or microbicide activity. In addition to have said properties, these salts are sufficiently water soluble with surfactant properties so that said aqueous solutions, which contain them, form a substantial amount of foam. These salts can hence be advantageously used in purifying or cleansing formulations of the skin, mucosa and the auricle. Therefore a further aspect of the present invention are the said cleansing or sanitizing formulations for the skin, mucosa or ear comprising at least one of said agents with bacteriostatic, mycostatic, yeaststatic and/or microbicide activity.

A further aspect of the present invention is a process for preparing the salt of formula which comprises the following steps: esterifying dimethylaminoethanol with a halide of formula RCOX', wherein X' is a halogen selected from chloride or bromide, optionally in the presence of a hydrogen ion acceptor, thus obtaining the ester of formula, wherein R has the aforesaid meanings; salifying the ester of formula by treating the reaction mixture derived from the first step in order to obtain the salts of formula.