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Patent Picks—Etyllinoleate, Dibenzoyl Peroxide, Pentane-1,5-Diol, Microcapsules and More for Treating Acne
By: Katie Anderson (Schaefer), Cosmetics & Toiletries magazine
Posted: July 12, 2011
page 2 of 5
An active agent delivery composition is provided that allows topical delivery of active agents including vitamin A and its derivatives. A polyhalogenic vehicle such as methoxyonafluorobutane or ethoxyonafluorobutane serves as a coupler for an active agent and a silicone carrier so as to allow solubilization of active agents not normally miscible in silicones and providing a moisture maintaining composition. Lipophilic skin care active agents such as retinoids are generally applied topically to reduce the appearance of aging, for other cosmetic purposes, or to treat a skin condition such as acne.
Core stabilized microcapsules, method of their preparation and uses thereof
WIPO Patent Application WO/2011/080741
Publication Date: July 7, 2011
Assignee: Sol-Gel Tehnoloties Ltd., O Toledano, H Bar-Simantov, H Sertchook, S Fireman-Shoresh and D Marco-Dagan
The present invention provides core-stabilized microcapsules, wherein said core comprises at least one active agent encapsulated within a metal oxide shell, processes for their preparations, comparisons comprising them and uses thereof.
The present invention provides a process for preparing microcapsules having a core encapsulated within a metal oxide shell, said process comprising: preparing an o/w emulsion by emulsifying an oily phase comprising at least one active agent and at least one phase changing material in an aqueous phase, wherein at least one of said oily phase and aqueous phase comprise a sol-gel precursor; subjecting said emulsion to microcapsule forming conditions; thereby obtaining said microcapsules.
In a further aspect, the invention provides a method for treating a surface condition in a subject in need thereof, comprising topically administering to said subject a composition of the invention. The invention further provides a composition comprising microcapsules of the invention, for the treatment of a disease, disorder or condition selected from acne, infection, inflammation, puritis, psoriasis, seborrhea, contact dermatitis, rosacea and a combination thereof.