Patent Picks—Cassia Deposition, Warming Substrates, Sol-gel Particles and More

By: Rachel L. Grabenhofer, Cosmetics & Toiletries magazine

Posted: April 20, 2011

page 3 of 5

The described transdermal therapeutic system comprises: a) a pouch made of metallic foil, polymeric film, paper, laminates of these or a combination thereof, which is sealed thermally, ultrasonically by application of pressure, gluing or a combination thereof; for increasing the drug concentration at the vicinity of the skin via a layer that performs as a release liner; b) a scraper layer made of polymeric or metallic or non metallic powder or particles coated thereon; which assists in removal of dust, debris, dead cells etc., invariably present on the application site over the skin, thus assisting in better adherability and improved drug transfer flux characteristics; c) a backing layer, which is provided on the top of the pouch; to control the degree of occlusion selectively over the area of the patch; and d) an adhesive embedded with a drug mesh or net at the bottom that is in contact with the pouch; to provide for a physical shaping of the transdermal patch for it to stay in place on the skin thorough out the time period of its intended use. Finally, a built-in color coded indicative system is incorporated to visually cue the patient for the removal old and re-application of new patches. 

Application device for topical administration of pharmaceutical compositions and products
US Patent 7927034
Publication date: April 19, 2011
Assignee: Pharmakodex Ltd.

Disclosed in this patent is an applicator for applying a spreadable composition to the skin or other exterior region of a human or animal body, comprising means for receiving and carrying a unit or measured dose of the composition and a grip for enabling a user to grip and manipulate the applicator. The described grip and receiving means are arranged in such a way that the user is protected from inadvertent contact with a composition.

Methods for preparing nanotextured surfaces and applications thereof
US Patent 7923075
Publication date: April 12, 2011
Assignee: The Hong Kong University of Science and Technology

This invention describes a rapid and inexpensive technique for generating nanotextured surfaces involving: a) the creation of a regular, nanometer-sized template by microwave assisted hydro- or solvo-thermal treatment of polymer films coated on surfaces, followed by b) a coating layer of metal, metal oxides, polymers and inorganic materials. The nanometer-sized polymer template could be removed to create regularly shaped, hollow nanostructures, e.g., nano-bottles, nano-bowls, nano-holes, etc.