Patent Picks—Copper-bound Botanicals, Skin Pigment Regulation, Antioxidants and More

By: Rachel Grabenhofer, C&T magazine

Posted: October 6, 2010

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Cosmetic Formulation to Treat Rosacea Telangiectasia
US Patent Application 20100247693
Publication date: Sept. 30, 2010
Inventors: JL Marini (San Jose, CA, US)

The present invention features novel cosmetic skin care compositions for improving the appearance of rosacea-affected skin. Specifically, the skin care compositions presented herein contain a synergistic combination of: azaleic acid; a retinoid, e.g. retinol; one or more vitamin K compounds; and peptides, for use in improving the appearance of rosacea-affected regions of the skin. The formulation is provided in a cosmetically acceptable vehicle(s), which may further comprise skin soothing/conditioning agents, and permeation enhancers, e.g. transcutol. Accordingly, the synergistic combinations of the active ingredients of the invention are formulated as skin care cosmetic compositions that can be applied directly to the skin so as to improve the appearance of skin texture and color. The compositions may additionally provide cosmetic benefit for acne, discoloration, oily skin, aging skin, spider veins and sun damage.

Cholesterol Sulfate and Amino Sugar Compositions for Enhancement of Stratum Corneum Function
US Patent Application 20100247692
Publication date: Sept. 30, 2010
Inventors: DH Maes (Huntington, NY, US) and J  Zecchino (Closter, NJ, US)

The present invention provides compositions containing a mixture of cholesterol sulfate and an exfoliant. The exfoliant can be N-acetyl-D-glucosamine, N-acetylgalactosamine, or a combination thereof. The combination of cholesterol sulfate with the exfoliant surprisingly enhances the skin barrier even though the activity of each of the components is opposite the other. In addition, because of the ability to enhance or repair the skin barrier function, methods of maintaining or improving a healthy skin barrier are included in the present invention by apply to the skin an effective amount of the mixture of cholesterol sulfate with the exfoliant. The mixture can also be useful in treating or preventing damage to the skin, where the damage is caused by a comprised skin barrier function. As a result of improved skin barrier function, the appearance of lines and wrinkles is generally reduced; rough and dry skin conditions are also improved.

Composition, for Prevention and/or Treatment of Pruritus, Containing Acacai Bark Derivative
US Patent Application 20100247690
Publication date: Sept. 30, 2010
Inventors: Y Nakamoto (Hiroshima, JP) and K Ono (Hiroshima, JP)

This patent disloses a composition containing an acacia bark derivative that is useful in preventing and/or treating pruritus. The composition prevents the onset of pruritus and cures or alleviates it by demonstrating antipruritic and/or itching relief effects. In addition, the composition is very safe and has less potential for adverse side effects and the like even if taken for a long period of time.

Skin Treatment Compositions Containing Copper-Pigment Complexes Bound to Botanicals 
US Patent Application 20100247628
Publication date: Sept. 30, 2010
Inventors: PL Dorogi (Easton, PA, US), DB Vasily (Bethlehem, PA, US) and JP Mccook (Frisco, TX, US)