Personal Care Technologies Appearing in Recent Scientific and Patent Literature

Mar 1, 2008 | Contact Author | By: Charles Fox, Independent Consultant
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Title: Personal Care Technologies Appearing in Recent Scientific and Patent Literature
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Skin and Skin Care SCI mildness studies: Ghosh et al. have studied the mildness of sodium cocoyl isethionate (SCI) on the skin barrier via an in vitro investigation of the relative sizes of the SCI micelles and skin pores.1 SCI is an important surfactant ingredient in mild, synthetic detergent (syndet) cleansing bars, and studies have shown it is more mild and less damaging to the skin barrier than soaps and surfactants such as sodium dodecyl sulfate (SDS).

Researchers have shown that in aqueous solutions SDS forms smaller micelles than the pores in the stratum corneum (SC), and as a result, the SDS micelles can contribute to SDS skin penetration and induce skin barrier perturbation. In the presented research, the authors attempt to explain the well-documented skin mildness of SCI by examining the size of the SCI micelles relative to that of the aqueous pores in the SC. For this purpose, in vitro mannitol skin permeability and average skin resistance measurements were taken after skin was exposed to an aqueous SCI solution. In this context, the hindrance of solution transported though the pores in the SC was measured.

The studies demonstrated that an SCI micelle radius of 33.5 ± 1 Å, as determined using dynamic light-scattering measurements, showed significant steric hindrance and could not penetrate into the SC through aqueous pores with an average radius of 29 ± 5 Å. The researchers believed that the inability of the SCI micelles to contribute to SCI skin penetration and associated skin barrier perturbation is responsible for the observed skin mildness of SCI.

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Formula 1. Cream type skin cleanser

 Formula 1. Cream type skin cleanser

Formula 2. Facial cleanser

 Formula 2. Facial cleanser

Formula 3. Skin-softening cream

Formula 3. Skin-softening cream

Formula 4. Hair dye cream

 Formula 4. Hair dye cream 

Formula 5. Cream hair dye

 Formula 5. Cream hair dye

Formula 6. Bleaching or coloring agent

 Formula 6. Bleaching or coloring agent 

Formula 7. Lipstick with inulin stearate

 Formula 7. Lipstick with inulin stearate

Formula 8. Powder foundation

 Formula 8. Powder foundation

Formula 9. Cake makeup foundation

 Formula 9. Cake makeup foundation

Formula 10. Sand repellent sunscreen

 Formula 10. Sand repellent sunscreen

Formula 11. Decorative nail enamel base coat

 Formula 11. Decorative nail enamel base coat

Formula 12. Anti-hair loss product

 Formula 12. Anti-hair loss product 

Formula 13. Night cream nanoemulsion

 Formula 13. Night cream nanoemulsion

Formula 14. Nonsticky glossy emulsion

 Formula 14. Nonsticky glossy emulsion

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