A Review of Anti-irritants, Part II: Moisturizer, Anti-irritant Efficacy and Overall Interpretation

Jun 14th, 2013

Howard I. Maibach, MD, and Hongbo Zhai, MD, University of California School of Medicine

Wash test method: Hannuksela and Kinnunen¹developed a wash test method to determine the effect of moisturizers in preventing irritant contact dermatitis (ICD). Twelve healthy female students washed the outer aspects of their upper arms with a liquid dishwashing detergent for one minute twice daily for one week. Eight commercial moisturizers were applied to the left upper arm just after each washing while the other arm was left untreated. During the second week, the left upper arm only was treated with the moisturizers twice daily.

Log in to view the full article

Researchers identified a notable rise in carbon monoxide (CO) levels, which correlated with a spike in AD, dermatitis and eczema-related dermatology clinic visits.

Air Pollution from Wildfires Stirs Skin Flare-ups in Northeastern U.S., Study Suggests

Air pollution from Canadian wildfires last summer reached the northeastern U.S. and stirred up skin conditions, a recent study suggests. In a related interview, Shadi Kourosh, M.D., advised consumers to wear mineral sunscreen and take other precautions.

PrimalHyal™ 50 Life, the virtuous revolution for Hyaluronic Acid

PrimalHyal™ 50 Life, the virtuous revolution for Hyaluronic Acid

PrimalHyal™ 50 Life, the virtuous revolution for Hyaluronic Acid and the skin barrier. Givaudan Active Beauty unveils PrimalHyal™ 50 Life, a transformational sustainability breakthrough in Hyaluronic Acid production.

This year, readers engaged in stories on regulatory updates and safety and trends in the industry.

2023 Wrapped: 10 of Cosmetics & Toiletries Top Stories of the Year

This year, readers engaged in stories on regulatory updates and safety and trends in the industry.

New research points to a signaling pathway that could explain many cases of itchiness on skin.

Did Researchers Just Solve Itchiness?

According to the authors, V8 stimulates PAR1, or "proteinase-activated receptor 1," causing spontaneous itching and resulting itch-related skin damage.

Metal nanoparticles such as gold have drawn attention in nanomedicine due to their low chemical reactivity and excellent biocompatibility.

Research Finds Gold Nanorods Block IR-A and Could Protect Against Thermal Aging

A study from researchers at the University of Suwon and Kumoh National Institute of Technology, both in the Republic of Korea, has uncovered the ability of gold nanorods to block IR-A. Findings suggest they could serve as actives to prevent thermal aging.

Shoko Hamada, of Kobayashi Pharmaceutical Co., explains her work to identify antimicrobial fragrance compounds during the IFSCC 2023 poster session.

[video] 4 Novel Effective Antimicrobial Compounds on IFRA's Transparency List

In this interview from the IFSCC 2023 poster session, Shoko Hamada, of Kobayashi Pharmaceutical Co., explains her research exploring antibacterial and antiviral properties of compounds on IFRA's transparency list, uncovering four with promising effects.

A double-blind, placebo-controlled, randomized four-way study investigated the effect of 12- week daily dietary supplementation with collagen and MSM on skin health.

Tosla Publishes Clinical Study on the Efficacy of Three Test Products

A double-blind, placebo-controlled, randomized four-way study investigated the effect of 12- week daily dietary supplementation with collagen and MSM on skin health.

The company establishes scientific partnerships with university research teams each year.

Silab Publishes Results of Research from University Partnerships

The company establishes scientific partnerships with university research teams each year.

C. acnes induced a large increase in lipids such as triglycerides, ceramides, cholesterol and free fatty acids.

How Metabolites from C. acnes Improve Barrier Function

Researchers recently uncovered how a common acne bacteria could actually help to improve barrier function.

In a world where societal beauty norms can lead to dissatisfaction and disapproval of one's own appearance, research presented by Ayuna demonstrated the transformative effect of skin care on our mental well-being.

Exploring Daily Facial Massage at IFSCC 2023

Poster presentations brought together innovators and researchers from the cosmetics industry to unveil first studies on the transformative effects of massage, and focused in this instance on improved skin concerns, sleep patterns and mental well-being.

The method heats long carbon chains from milk cartons, food containers and plastic bags then quickly cool them, turning them into surfactants to be used in soaps, detergents and more.

Virginia Tech Chemists Create Soap from Plastic Waste

The method heats long carbon chains from milk cartons, food containers and plastic bags then quickly cool them, turning them into surfactants to be used in soaps, detergents and more.