Topically-Applied Soy Isoflavones Increase Skin Thickness

May 6, 2003 | Contact Author | By: Schmid, D  ;Zülli, F
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  • Keywords/Abstract

Keywords: soybeans | isoflavones | genistein | estrogen | collagen | matrix metalloproteinase

Abstract: The placebo-controlled study in humans has shown that soy isoflavones have a potent effect on the improvement of skin thickness in aged skin. The authors discuss the possible mechanisms of action.

Epidemiological studies indicating as association between diet and disease led to the investigation of a series of bioactive plant compounds. In Japan, for example, the incidences of cardiovascular disease, hormone-dependent cancers (breast, uterus and prostate) and menopausal symptoms (osteoporosis and hot flashes) are all substantially lower than in western countries. The traditional Japanese diet includes a significant amount of soy-based foods such as tofu and tempeh.