Pollution and Aging: Antioxidants for Skin

November 4, 2011 | Contact Author | By: Jean-Francois Nicolay and Christophe Paillet, Exsymol S.A.M.
Close
Fill out my online form.
Save
This item has been saved to your library.
View My Library
(click to close)
Save to My Library
Title: Pollution and Aging: Antioxidants for Skin
cutaneous agingx pollutionx cell membranex lipid hydroperoxidesx toxic aldehydesx second toxic messengersx pseudodipeptidesx lipid peroxidase-like activityx
  • Article
  • Keywords/Abstract

Keywords: cutaneous aging | pollution | cell membrane | lipid hydroperoxides | toxic aldehydes | second toxic messengers | pseudodipeptides | lipid peroxidase-like activity

Abstract: Cell membrane-derived lipidic hydroperoxides, introduced into the skin by environmental stresses, seem to be key players in oxidative stress-mediated extrinsic aging. Imidazole-containing peptidomimetics can protect against their toxicity through a variety of mechanisms.

Among the numerous pathways and mechanisms involved in the complex phenomenon of aging, recent findings have designated oxidative processes as a major extrinsic cause.1, 2 Our skin is exposed daily to environmental stresses such as pollutants or UVB radiation that induce a number of oxidative insults primarily to the biological membranes of skin cells.