Recent in Method Development/Validation (page 1 of 3)

Scale-up Success: Untapping the Potential of Computational Fluid Dynamics

Scaling up cosmetic products to manufacturing facilities is a common cause of formulation difficulties. Computational fluid dynamics offer a means to model and troubleshoot potential problems in advance, and could become a standard tool to reduce production costs.

Countering P. acnes: In vitro Approaches to Anti-acne Testing

Acne is thought to be caused by the Propionibacterium acnes (P. acnes) bacteria, with widespread effects. The assays described in this article may provide a starting point with which to screen novel materials to treat the condition.

Scale-up Success Requires Compromise

The in-cosmetics technical session on scale-up success was, in and of itself, a scale-up success as it left standing room only for a crowd of attendees eager to learn tips, tricks and best practices.

[podcast] Probing Deeper to Further Skin Aging Research

Johnson & Johnson can see the future—of skin aging, that is. How? Using a novel imaging technique, which Tracy Wang, Ph.D., presented at the SID meeting last April and describes in this interview. Listen now!

BASF-Poietis Deal to Take 3D Bioprinting to Cellular Depths

BASF and 3D bioprinting expert Poietis have big plans to advance skin care. In an extended agreement, the two will collaborate to optimize the 3D bioprinting of skin equivalent models to study the effectiveness of actives.

Are Your Sunscreens Infra-ready? New In vitro Method Puts Data Behind the Claims

Considering more and more sun care products are claiming infrared (IR) protection, it is important to standardize the parameters by which they are evaluated. Since IR-A and IR-B are the most implicated in skin damage, a test method was developed based on these wavelengths, as described here.

New Ideas on Hair Breakage: Mending Existing Flaws

Our historical beliefs as to the causes of hair breakage have been largely shaped by findings from testing approaches. More recently, an alternate mechanical testing technique, fatigue testing, has been changing our perspective on this topic.

[podcast] Senescence to Understand Aging in Hair

Aging is a common denominator across not just cultures but substrates. Here, Alison Pawlus, Ph.D., of Aveda, describes a test based on cell senescence to measure the effects of aging in hair and identify ways to mitigate them. Listen now!

How Damaged is Hair? Part III: Better Defining the Problem

By identifying elements at the heart of technical issues in hair, product developers will uncover options to consider for improving its health and appearance. Completing our three-part series, this final piece on hair damage provides insight on new ideas and strategies for problematic hair.

How Damaged is Hair? Part II, Internal Damage

This article is part II in our series on hair damage. It explains the internal cortex structure of hair is not easily visible, and that various mechanical tests can yield different conclusions. Here, tests are described that can show changes to the internal cortex structure and their impact on hair’s mechanical properties.

Untouched, 'Primitive' Microbiome Sets the Skin Health Benchmark

As it turns out, on skin, the more "bugs," the better; and cosmetics could be negatively affecting their diversity. New research from the UK compared microbiomes to set a "healthy skin standard," against which the effects of products can be measured, in the future.

Depth Perception: FTIR Reveals Devices Deliver Actives and Hydration Deeper

The deposition, delivery and penetration of actives are key to the success of skin care products and consequential to their efficacy. This paper explores ATR-FTIR imaging to compare the penetration of actives into skin via two application methods and their impact on skin hydration.

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