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Recent in Testing (page 31 of 32)

Permeation Method Developed As Alternative to Franz Cell

Aug 1, 2012

Pion Inc. has introduced a test method that predicts the permeability of drugs and dermal formulations through the human skin without the cost and low throughput restrictions of the Franz cell chamber.

NICEATM Calls for Scientific Experts and Data on Eye Testing

Jul 17, 2012

The National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) is looking for scientific experts and data for a scientific review panel.

Large-scale Screenings of Botanical Ingredients: Challenges and Opportunities

Jul 3, 2012 | Patricia da Luz Moreira, PhD, Natura Inovaçã e Tecnologia de Produtos Ltda., São Paulo, Brazil

Botanical ingredients are interesting for their unique and complementary chemical diversities yet they are criticized for these very traits, which make quality assurance, reproducibility and good phytochemical characterization—required for successful high throughput screening, difficult. This article discusses these challenges as well as the benefits of large-scale screenings of botanical extracts that are currently used or developed for cosmetic product development.

A Synthetic Tissue-based In vitro Ocular Irritation Assay

Jul 3, 2012 | Stewart J. Lebrun, Lebrun Labs, CA USA

The testing of personal care products for ocular irritancy ensures their safety, proper labeling and consumer satisfaction. In relation, there is a current demand for animal-alternative tests. Thus, described here is a method using synthetic tissue to test for mild, moderate and severe ocular irritation, including data validating this method as an effective means to screen products.

Brookfeld Designs Fixture to Test Cosmetic Pencil Hardness

Jun 27, 2012

Brookfield Engineering Laboratories has has added a fixture to its offering that tests the hardness of cosmetic pencils.

Substantiating Skin Care Claims

May 4, 2012

Evalulab will discuss its clinical testing services specializing in the safety and efficacy of skin care products, to root product claims in science.

A Novel Method to Measure and Pre-select Functional Filler Pigments

May 3, 2012 | Miriam Becker, Christoph Schmidt, PhD, Veronika Hochstein and Xenia Petsitis, Merck KGaA, Darmstadt, Germany

Functional filler pigments play an important role in adjusting optical properties such as transparency and soft focus effects in cosmetics. However, their suitability for specific formulas is not apparent until time-consuming tests using many different fillers have been conducted. Therefore, a new method to predetermine the soft focus effects of functional filler pigments is described here.

EPA, L'Oréal Collaborate to Build Animal-Alternative Test Methods

Mar 12, 2012

The US Environmental Protection Agency (EPA) and global cosmetic manufacturer L’Oréal announced a research collaboration to develop animal-alternative toxicity tests to ensure product safety.

New method to Reproduce In vitro Cosmetic Product Photostability Findings

Mar 1, 2012 | Marc Pissavini, PhD, Adeline Baud, Stéphanie Marguerie, Karine Desseille and Olivier Doucet, PhD, Coty-Lancaster

The present article describes a reproducible method for determining the photostability of sunscreen products. This method is based in part on the in vitro determination of the UVA protection factor as proposed by Colipa for the irradiation aspect, and on the spectroscopy of a sunscreen in dilute solution for the absorbance measurement aspect.

ICCVAM Recommends Non-animal Endocrine Disruptor Screening

Feb 20, 2012

The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) has recommended a non-animal test method to identify estrogen agonist and antagonist activity. In addition to recommending the test, ICCVAM also found the method to provide a number of benefits over the method currently employed in the United States.

Hair Color Vibrance Factor to Characterize Shine and Color Intensity*

Jan 5, 2012 | Timothy Gao, PhD; Peter Landa; Regan Tillou; and Kevin Gallagher, Croda Inc.

To evaluate the comprehensive effects of shine and color intensity in hair, a hair color vibrance factor has been developed to enable new claims for hair dye formulas and after-dye treatments. Experimental results described here show how varying the ingredients in shine spray and hair dye formulas affect this factor and correlate with subjective panelist assessments.

Public Comments Requested for Development of NICEATM-ICCVAM 2013-2017 Five-Year Plan

Dec 9, 2011

NIEHS and NICEATM invite public comments that can be considered by the ICCVAM and the agencies' program offices in updating the NICEATM-ICCVAM 2008-2012 Five-Year Plan to develop the 2013-2017 Five-Year Plan.

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