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527 Results

Section: Testing

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Pioneering Skin Testing: Download our Informative Poster

Experience the unmatched predictability of Strat-M® membrane – a synthetic, non-animal based model for transdermal diffusion testing.

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Breaking Through, Part II: Chemical Ingredient Delivery*

Chemical delivery systems use additional chemicals to introduce ingredients into the skin. This installment concludes our skin delivery series with a discussion on chemical penetration; part one covered physical delivery.

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[video] LC-MS/MS Applied to Cosmetic Ingredients

Liquid chromatography mass spectrometry (LC-MS) can serve as a foundation from which to build innovative cosmetic ingredients. In this video, scientists at Silab showed Cosmetics & Toiletries just how they implement it in their work.

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Bee Venom is Back in the Buzz

Bee venom is back, this time with data. According to a thesis from the University of Strathclyde, previous reports of its effects were anecdotal and incomplete. Now there's science backing it; especially in terms of safety.

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ROSS's Dual-shaft Mixer Provides Intense Shearing

ROSS has designed Model CDA-25, a dual-shaft mixer for increased shear and homogenization.

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Detecting Coral Stress in Response to Sunscreens

Metabolomics is at the heart of recent work published in Nature Scientific Reports, wherein an increase in a known steroid in coral was noted in the presence of three common sunscreen ingredients.

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Legislation Proposed in Wake of Asbestos Allegations

New legislation has been proposed to the U.S. House of Representatives after children's and tween's product retailer Claire's recalled several cosmetic products thought to contain asbestos.

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[podcast] CeraVe, Ingredients and Psoriasis Relief

"Ceramides, urea and salicylic acid ... are all going to have a lot of impact on the disease process," explained Neal Bhatia, M.D. This second in a three-part podcast series explores the CeraVe brand, ingredients and psoriasis relief.

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Editor’s Note: New Frontiers in Hair Follicles

Could the exosome be a new frontier for healthy hair? What about “growing” benefits within the fiber itself? These advances suggest hair is not as “dead” as we thought; or at the very least, the living portion can be influenced. This issue is focused on textured hair treatments and biology, emotional ties to hair, low-water surfactants, water resistance vs. rheology and more.

Testing SPF 15–100, Indoor vs. Outdoor

Lab tests on sunscreens show it takes more energy to produce mild erythema on protected skin than unprotected skin. Yet the FDA questions the need for SPFs higher than 50. In response, two outdoor studies were conducted using commercial products to challenge standing premises and determine if there is a measurable difference in an SPF 100 and SPFs of 50 or less.

Predicting the Percutaneous Penetration of Cosmetic Ingredients

While previous algorithms for predicting the skin absorption of permeants was based on in vitro data, the present article proposes a quantitative structure-activity relationship (QSAR) model based on in vivo human data. Here, a set of human in vivo data is described that provides entry into predicting the penetration of cosmetic ingredients.

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A Soft Touch—Concepts in Hair Softness

Softness technically seems the opposite of stiffness but measuring properties related to fiber stiffness is difficult due to hair’s anisotropic structure. And while hair is technically “softened” at elevated humidity, this is the definition of a “bad hair day.” Improving fiber flexibility without adversely impacting breakage seems a sound technical strategy... Click through to read more in the digital magazine.

CeeTox Expands In Vitro Capabilities with Acquisition

CeeTox has acquired assets of ADMETRx Inc. that allow it to expand its range of in vitro service offerings. Specifically, the acquired assets allow CeeTox to increase its existing Absorption, Distribution, Metabolism, Excretion (ADME) capabilities.

In Vitro Model for Decontamination of Human Skin

The present study utilized an in vitro model to compare the decontamination capacity of three model decontaminant solutions: tap water, isotonic saline and hypertonic saline. Human cadaver skin samples were dosed with radio-labeled [14C]-formaldehyde and the surface skin of each sample was washed after each exposure with one of the three model decontaminant solutions.

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Soothing Moves: Cannabis Sativa Cell Culture Alleviates Inflammation

The field cultivation of hemp is tasked by today’s large-scale demand. Here, a Cannabis sativa cell culture extract is proposed as a sustainable alternative. After initial characterization, the extract was tested as described here for efficacy against inflammatory markers for skin-soothing activities.

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Testing the Fate (and Exposure) of Cosmetic Ingredients

Risk and exposure go hand-in-hand. So when researchers dared to publish a new method to assess the exposure and fate of cosmetic ingredients, we couldn't help but give them exposure, in this review.

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Testing Tactics in Skin: Evaluating Radiance and Texture

Hydrated, even-toned skin with a natural glow, all indicators of health, has gained popularity in the last decade. This article explores the meaning of skin radiance, its relationship to texture and various ways to measure this desired attribute.

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Progressing Safety, Sustainability and Sincerity with Synthetic Ingredients

As consumers demand complete transparency that extends beyond labels and claims, brands need to provide comprehensive information on the entire supply chain and product lifecycle...

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