Patent Picks—Carotenoid SPF Boost, Antimicrobial Hops and Polylactide Delivery in Skin Care

Patent Picks are taken from publicly available sources, and review recent patents and patent applications in cosmetics, personal care and peripheral markets. This edition features technologies related to skin repair, protection and care.

Optimized hops for antimicrobial, anti-inflammatory and other benefits
US Patent PP23674
Publication date: June 18, 2013
Assignee: S.S. Steiner, Inc.

Described in this patent is a new and distinct aroma variety of hop plant, Humulus lupulus L., named "Delta." It is characterized by good a cone yield, nice aroma (mild citrus/spice), 1:1 ratio of alpha-acids to beta-acids, low CoH, high linalool, good storage stability, and resistance to hop powdery mildew. According to the inventors, hop plant parts, tissue cultures and extracts have bioactive properties, including antimicrobial, anti-oxidative, anti-inflammatory and antibiotic, among others. These may be used in herbal remedies; in antimicrobial preparations for food; or in non-food uses, such as fermentation processes, water treatment, and cosmetics; and in nutraceutical and in pharmaceutical applications.

1-aza-3,7-dioxabicyclo[3.3.0]octane compounds to extend fragrance perception
US Patent 8466294
Publication date: June 18, 2013
Assignee: Henkel AG & Co. KGaA

Herein are described 1-aza-3,7-dioxabicyclo[3.3.0]octane compounds, a process for their preparation, and their use as pro-fragrances; in washing and cleaning compositions, and fabric softeners; and cosmetics comprising them. The compounds prolong the scent perception of such compositions, as it has been found that bicyclic oxazolidine derivatives of scent aldehydes and scent ketones allow a reduction in vapor pressure of the scent aldehydes and scent ketones. Furthermore, the deposition of the bicyclic compounds on solid surfaces such as textiles, skin or hard surfaces can be improved.

Emulsifier systems containing organomodified siloxane block copolymers
US Patent 8466248
Publication date: June 18, 2013
Assignee: Evonik Goldschmidt GmbH

This invention relates to emulsifier systems comprising organomodified siloxane block copolymers and their use in the preparation of cosmetic, dermatological or pharmaceutical formulations, among others. It has been found that organomodified siloxane block copolymers prepared by a process described herein are high-performance emulsifiers, providing excellent emulsifying and stabilizing properties and imparting a velvety-silky skin feel. This is important as it increasingly important for cosmetic formulations to be spread easily and absorb well into the skin, leaving behind a smooth, soft, velvety impression. A further advantage of these emulsifier systems is their flexibility in terms of the properties of laterally modified siloxanes and of α,ω-modified siloxanes combined therein, allowing for a larger number of substitution options.

Polylactide compositions for delivery and more
US Patent 8466133
Publication date: June 18, 2013
Assignee: University of Geneva

According to this patent, polylactides can have molecular weights from about 2000 Da to about 250,000 Da, and are attractive for applications such as degradable sutures, pre-formed implants and compounds for drug delivery, e.g., sustained release matrices. Described herein are compositions and methods relating to polylactides for use in drug delivery, wherein an organic solvent is not required. They can be administered intradermally, transdermally, topically, mucosally, orally, locally, etc., in creams, lipid compositions (e.g., liposomes), ointments, pastes, powders, etc. Transdermal administration may also comprise the use of a patch to supply one or more active substances at a predetermined rate and in a continuous manner over a fixed period of time.

Nucleic acid-encoding peptides for skin healing, anti-aging
US Patent 8466106
Publication date: June 18, 2013
Assignee: Trustees of Tufts College

The present disclosure relates to protein and peptide chemistry; particularly, compounds and compositions, and uses thereof for promoting and inhibiting angiogenesis. The peptides described include the SEQ ID NOs: 1-4, which promote angiogenesis and cell proliferation. Further, the anti-angiogenic compounds include antisense oligonucleotides that hybridize or are complementary to the polynucleotides of SEQ ID NOs: 5-16, and the like. These isolated and purified peptides can be used to treat burns, cuts and scrapes; contusions, including oral and otolaryngological wounds; wounds that are caused and treated by plastic surgery; bone damage; or individuals prone to hypertrophic scarring, such as keloid scarring. They may also be used for treating sun-damaged skin, wrinkles, promoting hair growth, as a haemostatic agent, or as a medium for growth of cells and cultures.

Antimicrobial cationic peptides
US Patent 8466102
Publication date: June 18, 2013
Assignee: Carrus Capital Corporation

This invention provides compositions and methods for making and using therapeutic formulations of antimicrobial cationic peptides. These formulations may be used in the treatment of microorganism-caused systemic or localized infections, such as a septicemia or acne. They may also be used as surface disinfectants, coatings, in water purification, as constituents of shampoos and soaps, in food as preservatives, as cosmetic preservatives and more.

Sunscreen compositions with SPF enhancer
US Patent 8465729
Publication date: June 18, 2013
Assignee: Playtex Products, Inc.

This patent discusses a photo-protective composition that has a synergistic combination of at least one sunscreen agent and at least one carotenoid, resulting in a composition with an increased SPF, compared to that without the synergistic combination. Preferably, the composition also has at least one of the following additional components: emulsifier, emollient, skin-feel additive, moisturizing agent, film-former/waterproofing agent, pH adjuster/chelating agent, preservative, or any combination thereof.

Topical, plant-derived, spider vein skin treatment
WIPO Patent Application WO/2013/086518
Publication date:June 13, 2013
Assignee: Mary Kay Inc.

Disclosed herein is a composition that includes one or more of: Centella asiaclico, Vitis vinifera seed, magnolia bark, Camellia sinensis and/or dihydroxymethylchromone, and is used to treat telangiectasia. Telangiectasia is the dilatation of small blood vessels near the surface of a person's skin, visibly expressed as red, blue, purple or blotchy skin. In some instances, the dilated blood vessels appear in a branch-like, matting, linear or spider web-like pattern, thus commonly referred to as "spider veins." Current methods of treating spider veins include sclerotherapy, surgery, radiofrequency and laser ablation, which can cause damage to skin and often require professional assistance. In response, this combination of ingredients has been found to effectively treat telangiectasia or spider veins topically. In addition, the composition can moisturize the skin.

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