EGT is widely distributed in both the plant and animal kingdoms. It is preferentially accumulated in organs, cells and secretions predisposed to high levels of oxidative stress and inflammation such as liver, kidneys, erythrocytes, eye lens and seminal fluid. It can enter the cells and mitochondria through the transporter OCTN-1, directly scavenging ROS, and playing the role of antioxidant and mitochondrial protection.
Figure1 The function of EGT in the cell
Previous studies have showed that EGT is more efficient in inhibiting lipid peroxide formation than coenzyme Q10 and Magnesium Ascorbyl Phosphate (MAP), removing H2O2 and UVA-induced peroxides than idebenone, scavenging hydroxyl radicals 90% higher than Trolox, clearing ROO- 550% better than GSH. It can improve the activity of glutathione reductase and superoxide dismutase.
How to get EGT?
Bloomage collected natural Hericium erinaceum and Tricholoma matsutake from Shangri-La forest, which was extracted and purified mycelium of the two mushrooms. By multifermentation, BioyouthTM-EGT is obtained. In addition to EGT, it also contains β-glucan, peptides, amino acids, polysaccharides, etc. Sprayed BioyouthTM-EGT with HA (MW < 5000Da) and trehalose, we get BioyouthTM-EGT Pro.
- Protect the DNA and mitochondria in skin cells from UV damage.
- Antioxidant-Scavenge free radicals,
- Antioxidant-Improve the activity of SOD (Superoxide dismutase).
- Antioxidant-Inhibit lipid peroxidation.
- Increase cell activity, reduce apoptosis.
- Reduce pigmentation, anti-aging.
In vivo test showed when compared with the control group，0.5% BioyouthTM-EGT Pro can reduce brown spots by 10%, UV spots by 7%, fishtail lines by 8%, improve skin moisture by 15% and skin elasticity by 20% after 4 weeks’ application (see Figures 2-8).
Figure 2 Brown Spots of the right side of face before (Left) and after (Right) 4 weeks’ application.
Figure 3 UV Spots of the right side of face before (Left) and after (Right) 4 weeks’ application.
Figure 4 Fishtail lines of the right side of face before (Left) and after (Right) 4 weeks’ application.
Large fungi such as mushrooms are a valuable resource. Consumers think mushrooms can help the body adapt to physical and mental stress. With that, BioyouthTM-EGT Pro is a natural and effective antioxidant and anti-aging product fermented from mushrooms, and this active can meet the needs of cosmetic manufacturers and consumers in all aspects.
Bloomage has more than 30 years’ fermentation experience. We will continue to explore the great potential of effective bioactive ingredients to bring beauty, health and happiness to consumers.
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