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Method Development/Validation

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Apr 21, 2014 | 02:45 PM CDT

Review and Modern Advances of Retinoids for Cosmetics

By: Steven Isaacman, PhD, and Michael Isaacman, Ph…

For skin cancer, skin aging and acne, retinoids have proven both preventive and therapeutic. Successful efforts toward more bioavailable vitamin A derivatives and retinoid formulations have increased their use for cosmetic benefits. Recent work to further optimize retinoids and reduce their side effects has yielded a new generation of promising molecules, described here.

Apr 21, 2014 | 02:15 PM CDT

Molecular Biology in Future Skin and Hair Care

By: Howard Epstein, PhD, EMD Chemicals, Philadelph…

Techniques developed in the field of molecular biology are currently being used to screen cosmeceutical ingredients for skin and hair care applications. New findings are published on a daily basis, providing insight with respect to future innovations for skin and hair health and appearance. Several relevant developments are reviewed here.

Apr 21, 2014 | 01:32 PM CDT

Understanding Fragrance Allergy, Is Fragrance-free Always Necessary?

By: Howard I. Maibach, MD, University of Californi…

This article reviews studies to diagnose allergic contact dermatitis due to fragrance, including a patch test designed to measure such. Limitations of patch testing, the relevance of fragrance concentration in products, use testing of common consumer products, and dermatologist recommendations to manage fragrance contact allergy also are discussed.

Apr 21, 2014 | 12:07 PM CDT

Fatty Acid Bile Acid Conjugates—Hypothesis for Skin Anti-aging and Anti-acne Effects

By: Nava Dayan, PhD; Dr. Nava Dayan LLC, NJ, USA; …

Fatty acid bile acid conjugates (FABACs) have been found to affect skin by enhancing ATP-binding cassette (ABCA1) cholesterol transporter and competitively inhibiting stearoyl-CoA desaturase (SCD1) enzyme. Based on the mechanisms involved, detailed here, the authors developed a new FABAC and tested it in vitro. Results suggest its potential as an anti-aging and anti-acne active.

Apr 21, 2014 | 11:22 AM CDT

Lead, Aluminum and Parabens: Myths in Cosmetics

By: Chris Flower, PhD, and Emma Meredith, PhD; Cos…

Cosmetic companies comply with strict ingredient regulations and stay abreast of the latest scientific studies to ensure that their products are safe and efficacious. Yet, rumors still abound about cosmetic companies intentionally including toxic chemicals. This column looks into those myths, separating fact from fiction.

Apr 21, 2014 | 11:00 AM CDT

Turbulence in Emerging Markets But Cosmetics Will Prevail

By: Rob Walker, Euromonitor International

According to the latest forecasts from Euromonitor International, spending on beauty and personal care in the emerging markets will be higher than in the developed markets by 2018. A year ago, this power shift had been expected to take place in 2016.

Apr 18, 2014 | 04:52 PM CDT

Novel Azobenzene Compound to Extend and Reactivate UV Protection

By: Jin-Ye Wang, PhD, and Shengyong Geng, Shanghai…

Two azobenzene compounds were synthesized and combined in liposomal membranes. Their physico-chemical properties and biocompatibility were evaluated. The safer one was chosen, and its protective function for UVA and UVB were tested in vitro and in vivo. This azobenzene liposomal formulation provided good efficacy with longer shelf life, which could be utilized as a novel kind of repeated UV absorber.

Apr 18, 2014 | 04:20 PM CDT

Approaches and Issues in Powder Formulations

By: Peter Tsolis, The EstĂ©e Lauder Companies, Melv…

Powder cosmetic products (both pressed and loose) include foundations, eye shadows, primers, blushes, bronzers and all-over shimmer powders. Though the raw materials used in them often are similar, the processing, texture, packaging, applicators and application, along with color development, vary for each type. These variations are described here.

Apr 17, 2014 | 10:48 AM CDT

Symrise Seeking to Acquire Diana Group

By: Abby Penning

Symrise submitted a binding offer and has entered into exclusive discussions with the owners of Diana Group with regards to the acquisition of Diana Group.

Apr 15, 2014 | 04:17 PM CDT

Dove Experiment Shows Beauty is Mind Over Matter

By: Abby Penning

A social experiment conducted by Unilever brand Dove revealed that 80% of women feel anxious about the way they look. The study also highlighted how the right state of mind can unlock a feeling of beauty in women.