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New in Method Development/Validation (page 190 of 200)
Jul 03, 2012 | 03:07 PM CDT
By: Rachel L. Grabenhofer
From an insider’s view, safety testing is an assumed step in the development of any product on the market. This puts the pressure on analytical and quality control efforts behind the scenes to ensure that ingredients and products meet or exceed expectations. In doing so, theoretically, no one else has to give it a second thought. For those who must give it considerable thought, this edition features two articles on testing, among other topics.
Jul 03, 2012 | 03:00 PM CDT
By: Patricia da Luz Moreira, PhD, Natura Inova&cce…
Botanical ingredients are interesting for their unique and complementary chemical diversities yet they are criticized for these very traits, which make quality assurance, reproducibility and good phytochemical characterization—required for successful high throughput screening, difficult. This article discusses these challenges as well as the benefits of large-scale screenings of botanical extracts that are currently used or developed for cosmetic product development.
Jul 03, 2012 | 02:51 PM CDT
By: Stewart J. Lebrun, Lebrun Labs, CA USA
The testing of personal care products for ocular irritancy ensures their safety, proper labeling and consumer satisfaction. In relation, there is a current demand for animal-alternative tests. Thus, described here is a method using synthetic tissue to test for mild, moderate and severe ocular irritation, including data validating this method as an effective means to screen products.
Jul 03, 2012 | 02:46 PM CDT
From Elastin to Elastic Fibers, Part I: The In vitro Effects of a Natural Dipeptide on the Biological Cascade
By: Philippe Mondon and Ada Andre - Sederma, Franc…
The peptide N-Acetyl-Tyr-Arg-Hexadecylester (NATAH) was found to stimulate the synthesis of tropoelastin in cultured human dermal fibroblasts as well as augment the activity of all important actors in the assembly of elastic fibers, including Fibrillin 1, Fibulin 5, Decorin, LOX and Transglutaminase, among others. This is shown here both in monolayer cell cultures and in a 3D skin model.
Jul 03, 2012 | 02:39 PM CDT
By: Luigi Rigano, PhD, Institute of Skin and Produ…
Many dermatological diseases such as athlete’s foot occur because the feet spend long spans of time in a warm, dark and humid environment. While there are several foot diseases related to diabetes, this column will focus on the development of foot care formulae designed for cosmetic treatments.
Jul 03, 2012 | 02:32 PM CDT
By: Katie Anderson (Schaefer), Cosmetics & Toiletr…
Mihaela Leonida, PhD, a professor of chemistry at Fairleigh Dickinson University, investigated the antibacterial properties of chitosan for cosmetic and pharmaceutical uses. She found that the material exhibited enhanced effects after being nano-sized.
Jul 03, 2012 | 02:23 PM CDT
A Dermatological View—Exploring Potential Differences in Percutaneous Penetration and Barrier Function Between Individuals of Different Ethnicity or Skin Color
By: Elodie Metral and Howard I. Maibach, MD, Unive…
The current understanding of percutaneous penetration and parameters that can influence it remains a sub judice area. Ethnicity or pigmentation, for instance, can be implied in percutaneous absorption for which several studies, described here, have been conducted to clarify their roles.
Jul 02, 2012 | 11:52 AM CDT
HallStar has created a polyester that allows formulators to combine active ingredients that have previously been considered too photo-unstable to be effective.
Jul 02, 2012 | 08:51 AM CDT
In a response to continued growth, Grant Industries is expanding and adding a 100,000 ft2 manufacturing facility in northern New Jersey.
Jun 29, 2012 | 08:17 AM CDT
A study conducted by Johns Hopkins Children's Center and funded by the National Institutes of Health supports the common "hygiene hypothesis" that some antibacterial chemicals and preservatives in hygiene products may make children more susceptible to food and environmental allergens.