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Method Development/Validation

New in Method Development/Validation (page 15 of 200)

Apr 22, 2014 | 12:26 PM CDT

Octocrylene Concerns Flag Industry's Attention

By: Rachel L. Grabenhofer, Cosmetics & Toiletries…

The industry reacts to a new study published in Contact Dermatitis reviews reports of the UV absorber octocrylene for its potential to cause photo contact allergy.

Apr 22, 2014 | 11:45 AM CDT

Phenoxyethanol as a Safe and Important Preservative in Personal Care

By: John Krowka, PhD, and Linda Loretz, PhD, Perso…

The effective preservation of personal care products and cosmetics is vitally important to inhibit microbial growth. Phenoxyethanol has a long history as an effective preservative, with well-documented human and environmental safety profiles. This is a valuable option in formulators’ and microbiologists’ toolboxes for safe and effective control of microbial growth, as is reviewed here.

Apr 22, 2014 | 10:36 AM CDT

Green Materials Featured at Sustainable Cosmetics Summit (15-17 May)

Sustainable Cosmetic Summit

For the first time, a summit will look at the entire supply chain of green cosmetic ingredients: from the sourcing of agricultural materials, processing methods, sustainability standards, ingredient authenticity, to the formulation and marketing in cosmetic products.

Apr 21, 2014 | 05:34 PM CDT

Patent Picks: Soft Hair Hold, Barrier Function and More

By: Cosmetics & Toiletries editors

Patent Picks are compiled by the editors from publicly available sources. This edition features the latest inventions related to an array of topics, ranging from soft hold in hair and barrier function in skin, to methods for quantifying hairs, devices for body contouring, processes to produce melanin, improving nail polish films, and more.

Apr 21, 2014 | 04:19 PM CDT

Correlating Aging with Skin’s Mechanical and Optical Properties

By: Olga Freis, PhD, Gilles Perie and Andreas Rath…

The aim of this study was to monitor the evolution of biomechanical and optical properties of the skin with aging. Different biophysical parameters were measured, including skin: elasticity and firmness, color, brightness, fluorescence emission, sebum content, hydration and pH. A significant evolution of the evaluated parameters with aging was observed.

Apr 21, 2014 | 03:30 PM CDT

Proposed Method to Evaluate the Microbiological Stability of Cosmetics During Use

By: Nadine Bresciani, Valérie Poulet and Nathalie …

The authors propose an approach to assess the microbial stability of a product during use, referred to as the Microbiological Use Test (MUT), and apply this analysis in case studies to predict the microbiological risk of commercial products. The described test has been used successfully in the development of cosmetics.

Apr 21, 2014 | 02:45 PM CDT

Review and Modern Advances of Retinoids for Cosmetics

By: Steven Isaacman, PhD, and Michael Isaacman, Ph…

For skin cancer, skin aging and acne, retinoids have proven both preventive and therapeutic. Successful efforts toward more bioavailable vitamin A derivatives and retinoid formulations have increased their use for cosmetic benefits. Recent work to further optimize retinoids and reduce their side effects has yielded a new generation of promising molecules, described here.

Apr 21, 2014 | 02:15 PM CDT

Molecular Biology in Future Skin and Hair Care

By: Howard Epstein, PhD, EMD Chemicals, Philadelph…

Techniques developed in the field of molecular biology are currently being used to screen cosmeceutical ingredients for skin and hair care applications. New findings are published on a daily basis, providing insight with respect to future innovations for skin and hair health and appearance. Several relevant developments are reviewed here.

Apr 21, 2014 | 01:32 PM CDT

Understanding Fragrance Allergy, Is Fragrance-free Always Necessary?

By: Garrett Coman and Nicholas Blickenstaff, Unive…

This article reviews studies to diagnose allergic contact dermatitis due to fragrance, including a patch test designed to measure such. Limitations of patch testing, the relevance of fragrance concentration in products, use testing of common consumer products, and dermatologist recommendations to manage fragrance contact allergy also are discussed.

Apr 21, 2014 | 12:07 PM CDT

Fatty Acid Bile Acid Conjugates—Hypothesis for Skin Anti-aging and Anti-acne Effects

By: Nava Dayan, PhD; Dr. Nava Dayan LLC, NJ, USA; …

Fatty acid bile acid conjugates (FABACs) have been found to affect skin by enhancing ATP-binding cassette (ABCA1) cholesterol transporter and competitively inhibiting stearoyl-CoA desaturase (SCD1) enzyme. Based on the mechanisms involved, detailed here, the authors developed a new FABAC and tested it in vitro. Results suggest its potential as an anti-aging and anti-acne active.