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Jul 14, 2010 | 09:25 AM CDT
Tools to Predict, Assess and Standardize Successful Color Cosmetics
Cosmetic companies have borrowed quality control methods from other industries that have product attributes such as color, gloss and texture down to a science. Specialized in such areas, X-Rite has developed tools to enable cosmetic companies to predict future color trends as well as set standards by which future cosmetics will be benchmarked.
Apr 30, 2010 | 12:40 PM CDT
Evaluating 1,3-Propanediol for Potential Skin Effects
By: Leigh A. Belcher, Carl F. Muska, PhD, and Jose…
In the present article, the authors assess the skin irritation and sensitization potential of 1,3-propanediol (INCI: Propanediol). Results in animals and humans by acute or repeat exposure support a low potential of skin reactivity for the material. In addition, the skin reactivity potential in humans was found to be lower with 1,3-propanediol than 1,2-propanediol (INCI: Propylene Glycol).
Mar 30, 2010 | 01:39 PM CDT
Predicting the Percutaneous Penetration of Cosmetic Ingredients
By: Sara Farahmand, PhD, University of Cincinnati …
While previous algorithms for predicting the skin absorption of permeants was based on in vitro data, the present article proposes a quantitative structure-activity relationship (QSAR) model based on in vivo human data. Here, a set of human in vivo data is described that provides entry into predicting the penetration of cosmetic ingredients.
Mar 16, 2010 | 05:21 PM CDT
Is Cosmetic Science Really "Bad"? Part IV: How Scientific is Cosmetic Science?
By: Johann W. Wiechers, PhD, JW Solutions
Six questions from Michael Shermer’s Baloney Detection Kit have been discussed in this series. The results were not flattering for cosmetic science (read: cosmetic scientists) but cosmetic science did not score badly on all points. Questions seven and eight, described here, discriminate true science from borderland science and non-science or nonsense.
Feb 26, 2010 | 04:56 PM CST
Mechanisms of Tape Stripping and Protein Quantification
By: Ali Alikhan, MD, and Howard I. Maibach, MD
In this article, several methods to quantify the protein collected by tape stripping are described, including traditional gravimetric methods as well as novel colorimetric and visible spectroscopic techniques. Further, one colorimetric method is described to effectively determine the keratolytic efficacy of various materials in vivo, suggesting additional roles for this method.
Feb 19, 2010 | 11:53 AM CST
Testing in Cosmetic Valley
By: Elian Lati, Pascal Svinareff, Marc Feuilloley …
Raman spectroscopy and fringe projection are a few of the methods that have revolutionized the objectification market.
Oct 13, 2009 | 12:25 PM CDT
In the Land of the Blind: Applying a Single-blind Study to Finished Products
By: Johann W. Wiechers, PhD, JW Solutions
Following positive feedback from a previous column on the placebo effect, Wiechers readdresses clinical study design in relation to cosmetic claim substantiation—this time discussing when to perform double-blind studies and when to perform single-blind studies.
Aug 28, 2009 | 10:05 AM CDT
ECVAM Calls for Testing Experts
The European Centre for the Validation of Alternative Methods (ECVAM) is renewing its scientific advisory structure and is calling for life sciences experts interested in joining its ESAC or EEP groups.
May 04, 2009 | 04:30 PM CDT
In vivo Quantification of Corneocyte Lipids by Image Analysis
By: David Boudier, Nathalie Guichard, Josselin Bre…
In a new method described here by the authors, fluorescence emitted from samples and captured by image analysis is used to quantify the number of lipids present in the cornified cell envelope. This in vivo approach is fast and noninvasive and could be used to screen molecules for potential moisturizing and restructuring effects.
Oct 30, 2008 | 05:44 PM CDT
The Air Up There: Skin VOCs
By: Katie Schaefer, C&T magazine
In 2001, Japanese researchers reported that after the age of 40, some individuals develop a malodor known as “aging odor,” attributed to the presence of unsaturated C9, 2-nonenal. George Preti, PhD, a member of Monell Chemical Senses Center and an adjunct professor of dermatology at the University of Pennsylvania School of Medicine, was interested by this report and began to conduct research of his own.