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In vitro
New in In vitro (page 7 of 14)
Oct 09, 2009 | 10:29 AM CDT
Genetic Test for Alopecia Approved in Europe
The HairDX Genetic Test for Hair Loss, a genetic baldness test manufactured by HairDX LLC, is now available as a CE Marked product under the European In Vitro Diagnostic Directive.
Sep 08, 2009 | 06:15 PM CDT
Lasers to Improve Acoustic Imaging
US Naval Research Laboratory scientists are developing a technology using flashes of laser light to create underwater sound, which could improve acoustic imaging.
Aug 28, 2009 | 10:05 AM CDT
ECVAM Calls for Testing Experts
The European Centre for the Validation of Alternative Methods (ECVAM) is renewing its scientific advisory structure and is calling for life sciences experts interested in joining its ESAC or EEP groups.
Jun 30, 2009 | 02:44 PM CDT
Evaluating Water Permeability and Occlusion in Wound Dressings and Topical Cosmetics
By: Hongbo Zhai, MD, and Howard I. Maibach, MD, Un…
The present study uses an evaporimeter to measure the degree of water loss from in vitro skin samples covered by occlusive and semi-occlusive wound dressings to serve as a model for determining the effectiveness of occlusive cosmetic formulations. The purpose of this work was to develop a model for determining the effectiveness of occlusive cosmetic formulations.
May 21, 2009 | 11:58 AM CDT
Researchers Initiate Automation of Skin Model Production
Instead of just a single layer skin model of a single cell type, the researchers have access to a patent-protected skin model that consists of two layers with different cell types. The researchers liken this model to a perfect copy of human skin and are in the process of developing the first fully-automated process chain for manufacturing two-layer skin models.
May 04, 2009 | 04:36 PM CDT
DNA: Hard Evidence of Cosmeceutical Claims
By: Katie Schaefer, Cosmetics & Toiletries magazin…
To support finished product or raw material claims these two in vitro methods—the Affymetrix microarray and the Taqman Real Time Polymerase Chain Reaction (PCR)—measure the up-regulation or down-regulation of genes.
Apr 01, 2009 | 11:53 AM CDT
In Vitro Model for Decontamination of Human Skin
By: Hongbo Zhai, MD, University of California; and…
The present study utilized an in vitro model to compare the decontamination capacity of three model decontaminant solutions: tap water, isotonic saline and hypertonic saline. Human cadaver skin samples were dosed with radio-labeled [14C]-formaldehyde and the surface skin of each sample was washed after each exposure with one of the three model decontaminant solutions.
Feb 27, 2009 | 10:56 AM CST
Dermal Absorption Guidelines for Cosmetic Ingredients: An In Vitro Method
By: Nava Dayan, PhD, Lipo Chemicals Inc.
Ex vivo skin absorption studies measure the penetration and permeation of a compound to assess its safety, and can assist the formulator in increasing product efficacy and reducing toxicity. This review analyzes the currently available guidelines published by four major regulatory organizations to clarify important milestones in study design, data analysis and interpretation.
Feb 23, 2009 | 02:31 PM CST
Much Ado About Nothing: Cosmetics Testing with a Placebo
By: Johann W. Wiechers, PhD, JW Solutions
In this column, the author investigates the source of the placebo effect. In addition, he asks the question: Must cosmetics testing always incorporate tests against a placebo?
Jan 30, 2009 | 02:28 PM CST
Tape Stripping Method in Humans: Comparison of Evaporimetric Methods
By: Hongbo Zhai, MD, and Howard I. Maibach, MD, Un…
The current preliminary study compared the sensitivity and correlation of open chamber device and closed chamber device on a tape stripping human model. The amount of SC removed by tape stripping was also quantified with a protein assay method.