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New in In vitro (page 5 of 15)
Jul 13, 2012 | 09:41 AM CDT
The Personal Care Products Council (PCPC) is requesting public comments on its revised guidelines on the identification of dangerous microorganisms in personal care raw materials and finished products.
Jul 03, 2012 | 03:07 PM CDT
By: Rachel L. Grabenhofer
From an insider’s view, safety testing is an assumed step in the development of any product on the market. This puts the pressure on analytical and quality control efforts behind the scenes to ensure that ingredients and products meet or exceed expectations. In doing so, theoretically, no one else has to give it a second thought. For those who must give it considerable thought, this edition features two articles on testing, among other topics.
Jul 03, 2012 | 03:00 PM CDT
By: Patricia da Luz Moreira, PhD, Natura Inova&cce…
Botanical ingredients are interesting for their unique and complementary chemical diversities yet they are criticized for these very traits, which make quality assurance, reproducibility and good phytochemical characterization—required for successful high throughput screening, difficult. This article discusses these challenges as well as the benefits of large-scale screenings of botanical extracts that are currently used or developed for cosmetic product development.
Jun 04, 2012 | 03:24 PM CDT
By: R. Gopaul; D.G. Kern; H.E. Knaggs, PhD; and J.…
A blend of Narcissus tazetta bulb and Schizandra chinensis fruit extracts was developed for anti-aging benefits and tested for efficacy on a human skin equivalent. Results indicate it regulates the functions of youth gene clusters by increasing the activities found in younger skin and reducing the activities found in aging skin specific to structure, hydration, cellular proliferation and pigmentation.
Apr 09, 2012 | 03:30 PM CDT
By: Katie Anderson
After 25 years in the industry, Gavin Greenoak, managing and scientific director of the Australian Photobiology Testing Facility Pty., Ltd. (APTF), continues to strive for a better understanding of the interaction of light and the human body. Greenoak’s career began in cancer research, which has afforded him unique insight of skin biology and the effects of sun exposure.
Mar 01, 2012 | 04:37 PM CST
By: Marc Pissavini, PhD, Adeline Baud, Stéphanie M…
The present article describes a reproducible method for determining the photostability of sunscreen products. This method is based in part on the in vitro determination of the UVA protection factor as proposed by Colipa for the irradiation aspect, and on the spectroscopy of a sunscreen in dilute solution for the absorbance measurement aspect.
Feb 20, 2012 | 11:55 AM CST
The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) has recommended a non-animal test method to identify estrogen agonist and antagonist activity. In addition to recommending the test, ICCVAM also found the method to provide a number of benefits over the method currently employed in the United States.
Jan 05, 2012 | 04:33 PM CST
By: Timothy Gao, PhD; Peter Landa; Regan Tillou; a…
To evaluate the comprehensive effects of shine and color intensity in hair, a hair color vibrance factor has been developed to enable new claims for hair dye formulas and after-dye treatments. Experimental results described here show how varying the ingredients in shine spray and hair dye formulas affect this factor and correlate with subjective panelist assessments.
Oct 28, 2011 | 11:26 AM CDT
By: Katie Anderson (Schaefer), Cosmetics & Toiletr…
Today, product formulation goes hand in hand with efficacy testing, but nearly 40 years ago, when Sergio Nacht, PhD, started out in the personal care industry, it was a different story. Throughout his decades in personal care, Nacht has developed methodologies that have allowed the personal care industry to establish efficacy of a product and convey this to the consumer. He has also been instrumental in the increased efficacy of personal care products through sustained release.
Jun 30, 2011 | 11:49 AM CDT
Rapid Colorimetric Analysis of para-Phenylenediamine in Henna-based, Non-permanent Tattoo Color Mixtures
By: Christopher T. Krüger; Dirk W. Lachenmeier, Ph…
In some henna mixtures, para-phenylenediamine (PPD) has illegally been added and it is responsible for complications such as allergic contact dermatitis. While high-performance liquid chromatography has previously been used to detect PPD, a colorimetric method that is faster and portable, described here, has been developed. For product developers, this method can be used to evaluate henna plant extracts.