Recent in In vitro (page 5 of 9)

Improved UV Testing to Prevent Product Degradation

Atlas Material Testing Technology has launched the fourth generation of its SUNTEST CPS+ with improved features such as improved quality of light, an easier viewed larger display panel, eight user languages and two pre-programmed test methods.

Detecting Estrogenic Endocrine Disruptors in Personal Care Products and Supplements

Endocrine disruptor chemicals (EDCs) are a class of chemicals that has raised alarm for being linked to a wide variety of detrimental effects on human and wildlife populations, e.g., cancers, precocious puberty and obesity. Thus, there is a need to test personal care products and supplements for EDCs, which can be accomplished using the validated bioassay described here.

Stability Testing

Cosmetic companies support and conduct stability study programs because it is good business. Any improvement in stablity of a product is important for product performance, consumer satisfaction and economics.

Permeation Method Developed As Alternative to Franz Cell

Pion Inc. has introduced a test method that predicts the permeability of drugs and dermal formulations through the human skin without the cost and low throughput restrictions of the Franz cell chamber.

Large-scale Screenings of Botanical Ingredients: Challenges and Opportunities

Botanical ingredients are interesting for their unique and complementary chemical diversities yet they are criticized for these very traits, which make quality assurance, reproducibility and good phytochemical characterization—required for successful high throughput screening, difficult. This article discusses these challenges as well as the benefits of large-scale screenings of botanical extracts that are currently used or developed for cosmetic product development.

Hair Color Vibrance Factor to Characterize Shine and Color Intensity*

To evaluate the comprehensive effects of shine and color intensity in hair, a hair color vibrance factor has been developed to enable new claims for hair dye formulas and after-dye treatments. Experimental results described here show how varying the ingredients in shine spray and hair dye formulas affect this factor and correlate with subjective panelist assessments.

Lab Lessons—Wise Words From the Bench With Sergio Nacht, PhD

Today, product formulation goes hand in hand with efficacy testing, but nearly 40 years ago, when Sergio Nacht, PhD, started out in the personal care industry, it was a different story. Throughout his decades in personal care, Nacht has developed methodologies that have allowed the personal care industry to establish efficacy of a product and convey this to the consumer. He has also been instrumental in the increased efficacy of personal care products through sustained release.

Rapid Colorimetric Analysis of para-Phenylenediamine in Henna-based, Non-permanent Tattoo Color Mixtures

In some henna mixtures, para-phenylenediamine (PPD) has illegally been added and it is responsible for complications such as allergic contact dermatitis. While high-performance liquid chromatography has previously been used to detect PPD, a colorimetric method that is faster and portable, described here, has been developed. For product developers, this method can be used to evaluate henna plant extracts.

P&G Presents 'Omics' Findings in Acne, Male Grooming, Dandruff and Anti-aging

During the World Congress of Dermatology, Procter & Gamble Beauty and Grooming is presenting new findings in acne, male grooming, dandruff and anti-aging based on a broader "omics"—i.e., genomics, proteomics and metabolomics, research tool.

ICCVAM and NICEATM Hold Meeting on Endocrine Disruptor Test Method

ICCVAM and NICEATM will hold a peer review meeting on March 29-30, 2011, for an in vitro test method that determines if chemicals are endocrine disruptors.

A Review of Genomic Techniques in Cosmetics Testing

Genomics assists product developers in understanding the expression of specific genes and their relationship to particular skin attributes. This article reviews commonly used testing techniques, such as DNA microarray, RT-PCR, SAGE, northern blot and RNA sequencing, and describes their application in testing the effects of cosmetic ingredients and products on skin.

ISO Equips Formulators to Identify Low-risk Cosmetic Products

The International Organization for Standardization (ISO) has released an international standard that will assist the cosmetic industry in identifying those products that have a low potential for contamination.