Open Assay Models (Washing) for Evaluating Subclinical Irritant Dermatitis

May 6, 2003 | Contact Author | By: Howard I. Maibach, MD, and Veranne Charbonnier, University of California
Contact the Author
Save
This item has been saved to your library.
View My Library
(click to close)
Save to My Library
Title: Open Assay Models (Washing) for Evaluating Subclinical Irritant Dermatitis
washingx open assay modelsx irritant dermatitisx
  • Article

To avoid the acute irritation and dryness that a sincle occlusive surfactant application (24-h) patch tes4t may cause, and to more realistically approximate actual consumer use, an open assay model was chosen to define subclinical, non-erthematous irritation in the stratum corneum. The model evaluates irritation by using clinical and instrumental techniques, as welll as squamometry measurements obtained from skin strippings.

Excerpt Only This is a shortened version or summary of the article that appeared in the Dec. 1, 2001 issue of Cosmetics & Toiletries magazine. If you would like a copy of the complete article, please contact us at customerservice@cosmeticsandtoiletries.com.