Using Ultrasound Scanning to Characterize Colloidal Particles

May 1, 2008 | Contact Author | By: Malcolm Povey, Procter Department of Food Science and Lyn S. Daintree, PhD, Institute of Particle Science & Engineering
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Title: Using Ultrasound Scanning to Characterize Colloidal Particles
ultrasoundx colloidal particlesx stabilityx product characterizationx phase separationx
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Keywords: ultrasound | colloidal particles | stability | product characterization | phase separation

Abstract: Changes in the macroscopic nature of aqueous or colloidal formulations can lead to changes in the odor, appearance or feel of a product. Data presented in this article demonstrates ultrasound scanning to determine formulation shelf life and monitor product quality.

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Ultrasound scanning is a highly promising new technique for product characterization and stability determination of colloidal and aqueous-based formulations. The stability of colloidal and fluid/particle dispersions is of increasing importance to the cosmetic and personal care industry where differences in raw materials can affect the batch-to-batch quality of products. Additionally, product developers in the industry need tools to predict formulation stability to reduce development time.

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Phase and Amplitude in Sound

 Phase and Amplitude in Sound

Figure 1. Ultrasound lab instruments

Figure 1. Ultrasound lab instruments 

Figure 2. Schematic diagram

Figure 2. Schematic diagram 

Figure 3. Ultrasound measurements

Figure 3. Ultrasound measurements  

Figure 4. Ultrasound images

Figure 4. Ultrasound images  

Figure 5. Ultrasound scanning of a parenteral emulsion

Figure 5. Ultrasound scanning of a parenteral emulsion  

Povey: Ultrasound Footnotes

 a Acoustiscan Ultrasonic Profiler is a laboratory instrument currently manufactured on an ad hoc basis by the University of Leeds, UK.

b Leica Microsystems Heidelberg GmbH
 
c Tween20 (INCI: Polysorbate-20) is a product of Uniqema Americas. Tween is a registered trademark.

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