Recent in In silico/Modeling (page 1 of 2)

Molecular Modeling of Skin care Products: Application for the Design of Pepidomimetics

Molecular modeling has been used in the pharmaceutical industry for years to predict how a new molecule may work based on research conducted with molecules of a similar structure. The cosmetics industry has also begun to use this technology to predict the behavior of new molecules on skin and in skin care applications.

Using Ultrasound Scanning to Characterize Colloidal Particles

Changes in the macroscopic nature of aqueous or colloidal formulations can lead to changes in the odor, appearance or feel of a product. Data presented in this article demonstrates ultrasound scanning to determine formulation shelf life and monitor product quality.

Software Launches to Formulate for Efficacy

As many formulators know, creating an efficacious cosmetic formulation can be problematic, which is why Johann Wiechers, PhD, is launching a new software platform based on his “Formulating for Efficacy” strategy.

Updated Modeling and Simulation Platform for Chemists

A new software platform has been designed to improve the efficiency and effectiveness of chemical and materials research to increase research productivity and decrease time-to-innovation.

Researchers Develop Hair Counting Software

The company's software uses images captured by a small flatbed scanner pressed onto the skin.

Molecular Modeling of Skin care Products: Application for the Design of Pepidomimetics

Molecular modeling has been used in the pharmaceutical industry for years to predict how a new molecule may work based on research conducted with molecules of a similar structure. The cosmetics industry has also begun to use this technology to predict the behavior of new molecules on skin and in skin care applications.

Using Ultrasound Scanning to Characterize Colloidal Particles

Changes in the macroscopic nature of aqueous or colloidal formulations can lead to changes in the odor, appearance or feel of a product. Data presented in this article demonstrates ultrasound scanning to determine formulation shelf life and monitor product quality.

Biochip Takes the Next Step Toward Replacing Animal Testing

Researchers at Rensselaer, the University of California-Berkeley, and Solidus Biosciences Inc. have developed a biochip that can mimic the effects of metabolism and analyze materials for toxicity.

Compass: Direct Routes

Will a flourishing category ever chance revealing this truth behind naturals to consumers? Perhaps so, as the naturals market becomes more saturated and key manufacturers seek ways to drive consumer interest into new areas.

Computer-aided Formulating

Informatics techniques have been developed that are capable of manipulating huge data sets that underpin modern formulation—from mining for information, to analyzing vast amounts of data. This article highlights how the use of computer technology can increase the efficiency and efficacy of formulating.

Modeling UVB-induced Formation of Photoproducts in Human Keratinocytes

The authors describe a model to visualize the appearance of cyclobutane-pyrimidine dimers in the nuclei of normal human keratinocytes after UV irradiation. These dimers are one of the principal agents in DNA damage. The model can be used to assess the effect of a cosmetic ingredient on the formation of direct UV-induced lesions to DNA.

Measuring Reactive Oxygen Species in Skin with Fluorescence Microscopy

Several signs of skin aging have been attributed to the presence of free radicals. This paper discusses the application of two-photon fluorescence microscopy to determine the effects of sample formulations on the number of reactive oxygen species (ROS) formed in skin models.

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