Recent in Efficacy/Claims Substantiation (page 1 of 4)

Quantifying Wellness: Anti-aging Benefits Beyond Wrinkle Reduction

Rather than anti-aging claims, these authors sought to quantify well-being as it relates to the effects of a new active: centcyamine. The authors confirmed a correlation between well-being scores, instrumental observations, self-assessment and, indirectly, in vitro mechanistic data.

The Dirty Truth About Pollution-induced Skin Aging: The AhR Pathway Tells All

Studies have shown that exposure to airborne, traffic-related particulate matter (PM) is associated with increased signs of extrinsic skin aging.1-3 Using model particles as surrogates, these researchers developed an in vitro model to evaluate premature aging induced via the aryl hydrocarbon receptor (AhR) pathway. They found a new AhR antagonist could inhibit the up-regulation of genes indicative for premature aging.

Can Hair Follicles Be Printed?

A new partnership between L'Oréal and Poietis is giving it a shot.

A Sunny Proposition: The Effects of Sun on Hair

While not nearly as well-documented as skin, plenty of literature indicates the sun can have damaging effects on hair.

In vivo Delivery Confirmation: Measuring the Deposition of Salicylic Acid from Anti-acne Face Wash

Measuring the delivery of active ingredients is an important part of the product development process, and particularly desirable are non-invasive, in vivo methods. This work describes the use of fluorescence excitation emission matrices in vivo to measure the deposition of salicylic acid from anti-acne face wash products.

Wet Skin Factor for Sunscreens: An In vitro Method, Part II

Sunscreens designed for application to wet skin are popular in part due to convenience, skipping the drying step completely. In relation, these authors propose a new in vitro test to compare the wet skin factor of sun care products. Here, 20 products were tested and compared according to several conditions in order to define the best parameters for the method.

Wet Skin Factor for Sunscreens: An In vitro Method, Part I

Sunscreens designed for application to wet skin are popular in part due to convenience, skipping the drying step completely. In relation, these authors propose a new in vitro test to compare the wet skin factor of sun care products. Here, 20 products were tested and compared according to several conditions in order to define the best parameters for the method.

Heat Protection Getting Warmer: Specialty Silicones for Hair

The present study examines the ability of silicones to protect hair during heat styling, compared with other industry benchmarks and untreated hair. Also discussed are the mechanisms through which different silicones contribute heat protection in hair care products such as leave-in conditioners, serums and other product forms.

Nonreactive Paths to Internal Changes: Modifying Hair’s Structure from the Inside, Part 2

Scientific evidence suggests that nonreactive compounds have the ability to modify hair’s structure, providing formulators additional ways to craft products and worry less about hair damage.

VIDEO: P&G Scientists on Claims Substantiation in Anti-dandruff Care

Head & Shoulders recruits an army to prove the benefits its brand delivers to consumers. Hear more in this video.

How to Prove 'Rub-resistant' Sun Protection

Today’s consumers desire sunscreens that are not only more effective against UV radiation, but also provide water, sand, sweat and rub resistance. These authors propose a new in vitro test to assess and compare rub resistance factors, which they illustrate here by testing 20 sun care products.

Modifying Hair’s Structure From the Inside

Changing hair properties is a regular function of daily-use treatments. But what other methods can be used? Altering the hair’s internal structure may be the next way to achieve these changes.

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