Initial evaluation of the in vitro porcine skin model has demonstrated its feasibility and consequently led to the OECD guideline TG428. Fresh porcine skin, which has been reduced to horny layer and epidermis plus some dermal tissue, is often used to determine the percutanous absorption of test substances in different vehicles. Punched circular pieces of porcine skin are placed in suitable diffusion chambers for testing.
Comparing Methods to Measure Porcine Skin Integrity In Vitro
August 27, 2009 | Contact Author | By: S. Richert, A. Schrader and K. Schrader, Institut Dr. Schrader Creachem GmbH
Abstract: To confirm the integrity of porcine ski prior to penetration tests, published studies show that measuring transepidermal water loss, transdermal electrical resistance or caffeine penetration levels are often chosen techniques. New results demonstrate that
Z-COTE LSA provides broad-spectrum protection from long wave UVA rays and medium wave UVB rays by physically scattering, reflecting and absorbing solar radiation.
- Zinc Oxide
- UVA, UVB Sunscreen
- UVA Protection
- UVB Protection