Recent in Testing (page 8 of 20)

Proposed Method to Evaluate the Microbiological Stability of Cosmetics During Use

The authors propose an approach to assess the microbial stability of a product during use, referred to as the Microbiological Use Test (MUT), and apply this analysis in case studies to predict the microbiological risk of commercial products. The described test has been used successfully in the development of cosmetics.

Sandblasting to Improve the Reproducibility of In vitro Sunscreen Evaluation

SPF test results from substrates treated using a traditional sandblasting technique are compared with those from substrates treated using a new process. Based on the topographic control of 10 batches and 34 sunscreen evaluations, the authors concluded the new process had better topographic reproducibility, consequently improving the SPF repeatability and reproducibility in vitro.

Researchers Dig Deeper Into Relationship Between Bacteria and Atopic Dermatitis

Researchers from the Drexel University College of Medicine have established a clearer relationship between Staphylococci bacteria and the conditions atopic dermatitis (AD) and eczema.

Collagens I and III, and Elastin Activation for Anti-aging

As an alternative to semi-invasive facial rejuvenation techniques, the authors developed an active ingredient to reactivate senescent fibroblasts by stimulating metabolic pathways for collagens I and III, and elastin. The biological activity of the resulting ingredient is investigated here using in vitro models, ex vivo explants and human volunteers.

Measuring the Water Content of Hair

Consumers have demonstrated a clear desire for hair that isn’t “dried out” while also demonstrating a clear distaste for the effects of high humidity on hair. To find the balance in creating products, it is necessary to have an accurate means of measuring hair’s water content. This article describes equipment used to perform this task while highlighting experimental variables that can produce suspect results and lead to incorrect conclusions.

State of São Paulo in Brazil Bans Cosmetic Testing on Animals

This ban in the Brazilian state follows a ban from India, Israel and the European Union, as well as debate and potential regulation changes in countries like China.

‘Anti-imperfection’ Claims

Four tests can be undertaken to substantiate the claims covered in this article. Colorimetry analyzes pre- and post-product application skin tone. A Cutometer or dermal torque meter measures the rate of skin extension pre- and post-product treatment, and stratum corneum turnover tests and acute profilometry studies show the rate at which skin is renewed or changes in the evenness of skin occur.

Liverpool Student Develops Alternative to Draize for Testing Mascara Irritation

Researchers at the University of Liverpool have developed a testing method alternative to the Draize test for mascara eye irritation using protozoa rather than animals. In addition to the new method not using rabbits, it was found to be cheaper and more reliable.

Liverpool Student Develops Alternative to Draize Test for Mascara Irritation

Researchers at the University of Liverpool have developed a testing method alternative to the Draize test for mascara eye irritation using protozoa rather than animals. In addition to the new method not using rabbits, it was found to be cheaper and more reliable.

Measuring Hair Strength, Part II: Fiber Breakage

In the mechanical testing world, the tendency for materials to fail under a repeated stimulus is termed fatigue testing, and this article discusses this topic in relation to hair breakage. It will be shown that this alternative testing approach provides considerable insight into the cause of hair breakage, and subsequently allows for the identification of strategies for its minimization; it will also be demonstrated how learning this provides the underlying theory by which anti-breakage and even “strengthening” claims are crafted.

Measuring Hair Strength, Part II: Fiber Breakage

In the mechanical testing world, the tendency for materials to fail under a repeated stimulus is termed fatigue testing, and this article discusses this topic in relation to hair breakage. It will be shown that this alternative testing approach provides considerable insight into the cause of hair breakage, and subsequently allows for the identification of strategies for its minimization; it will also be demonstrated how learning this provides the underlying theory by which anti-breakage and even “strengthening” claims are crafted.

ICCVAM Requests Info on Skin Sensitization Testing

The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) has requested the submission of new science or information on alternative test methods or testing strategies for skin sensitization, as part of a plan of action to advance this area.

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