Recent in Testing (page 21 of 32)

TRI/Princeton Offers Hair Benchmarking Study to Share Testing Costs

This benchmarking study allows manufacturers to test hair products for conditioning, anti-breakage strengthening, and anti-static flyaway reduction with shared controls and labor to reduce costs by up to 57%. The company is accepting participants until Aug. 15, 2010.

CeeTox Expands In Vitro Capabilities with Acquisition

CeeTox has acquired assets of ADMETRx Inc. that allow it to expand its range of in vitro service offerings. Specifically, the acquired assets allow CeeTox to increase its existing Absorption, Distribution, Metabolism, Excretion (ADME) capabilities.

Researchers Advance Animal-alternate Test for Skin Sensitization

Researchers at the National Institute for Occupational Safety and Health and Portland State University have developed an animal-alternative test method to assess the potential for chemicals in consumer products to cause skin allergies.

Evaluating Essential Oils in Cosmetics: Antioxidant Capacity and Functionality

In the present work, the antioxidant capacities of three essential oils derived from basil and thyme were evaluated using a photochemiluminescence (PCL)-based assay. In addition, since the base formulation can affect the antioxidant activity of oils contained therein, ingredient interactions within final formulations were investigated.

Evaluating 1,3-Propanediol for Potential Skin Effects

In the present article, the authors assess the skin irritation and sensitization potential of 1,3-propanediol (INCI: Propanediol). Results in animals and humans by acute or repeat exposure support a low potential of skin reactivity for the material. In addition, the skin reactivity potential in humans was found to be lower with 1,3-propanediol than 1,2-propanediol (INCI: Propylene Glycol).

Predicting the Percutaneous Penetration of Cosmetic Ingredients

While previous algorithms for predicting the skin absorption of permeants was based on in vitro data, the present article proposes a quantitative structure-activity relationship (QSAR) model based on in vivo human data. Here, a set of human in vivo data is described that provides entry into predicting the penetration of cosmetic ingredients.

Is Cosmetic Science Really "Bad"? Part IV: How Scientific is Cosmetic Science?

Six questions from Michael Shermer’s Baloney Detection Kit have been discussed in this series. The results were not flattering for cosmetic science (read: cosmetic scientists) but cosmetic science did not score badly on all points. Questions seven and eight, described here, discriminate true science from borderland science and non-science or nonsense.

Mechanisms of Tape Stripping and Protein Quantification

In this article, several methods to quantify the protein collected by tape stripping are described, including traditional gravimetric methods as well as novel colorimetric and visible spectroscopic techniques. Further, one colorimetric method is described to effectively determine the keratolytic efficacy of various materials in vivo, suggesting additional roles for this method.

Microfluidic Testing for LLNA Replacement

The Hurel Corp. has developed a microfluidic, non-animal alternative to the LLNA and it has partnered with L’Oréal to make this approach a reality—in the form of a chip.

A Rapid and Sensitive In vitro Method to Ascertain Antioxidative Capacity*

New methodologies have recently been developed to determine antioxidant effects but they often require extensive training and are time-consuming to conduct. In the present article, however, the authors describe an in vitro method to detect the effects of antioxidant-containing formulations using photochemiluminescence to provide rapid, accurate and sensitive measurements.

Researchers Mimic the Lymphatic System in Animal Alternative Chip

A chip created by L'Oréal and Hurel Corp. is designed to replace the local lymph node assay, a test often performed on cosmetic raw materials. In addition to saving animals, the chip is also said to be less expensive than animal testing. Hurel developed the working microfluidic portion of the chip.

Updated Modeling and Simulation Platform for Chemists

A new software platform has been designed to improve the efficiency and effectiveness of chemical and materials research to increase research productivity and decrease time-to-innovation.

Can't find what you're looking for? Try searching, or looking through past issues.