Most Popular in Testing
- VIDEO: P&G Scientists on Claims Substantiation in Anti-dandruff Care
- 'Zapping' Sensitive Skin: Capsaicin Tests Show Embelia concinna Comforts Irritation
- How to Prove 'Rub-resistant' Sun Protection
- SPF Tests Reveal No Ideal In vitro Substrate Exists
- Evaluating 1,3-Propanediol for Potential Skin Effects
- Testing and Developing a Sugar-derived Surfactant Blend for Delicate Skin
- Zeta Potential and Particle Size to Predict Emulsion Stability
- Ranking Body Creams by Sensory Properties
- Can New Approaches Pave the Way for Better Toxicology?
- Preservative Efficacy Testing: Accelerating the Process
Recent in Testing (page 20 of 32)
Sep 22, 2010
Four test method evaluation reports are now available from ICCVAM that provide recommendations for performing eye safety testing more humanely, and for developing and using non-animal test methods and strategies. Among these reports, ICVAAM has recommended that a cytosensor microphysiometer (CM) test method may be used to screen surfactant-containing formulations such as personal care products for the ability to cause permanent or severe eye injuries.
Jul 30, 2010 | Philippe Mondon, Nada André, Emmanuel Doridot, Olga Gracioso and Karl Lintner, PhD, Sederma SAS
Aging influences cutaneous parameters that give rise to progressive changes in three skin chromophores, altering the visual homogeneity of skin. To address these changes, the authors developed and examined the effects of a complex based on Siegesbeckia orientalis and Rabdosia rubescens using a novel skin imaging technique.
Jul 14, 2010
Cosmetic companies have borrowed quality control methods from other industries that have product attributes such as color, gloss and texture down to a science. Specialized in such areas, X-Rite has developed tools to enable cosmetic companies to predict future color trends as well as set standards by which future cosmetics will be benchmarked.
Jul 9, 2010 | Johann Wiechers, PhD, JW Solutions
Here, industry expert Johann Wiechers, PhD, discusses the frequent use of percentages by toxicologists to calculate skin penetration. To relate this discussion to modern day events, Wiechers describes the skin penetration of orange paint, used by fans of the Dutch national football team.
Jun 25, 2010
This benchmarking study allows manufacturers to test hair products for conditioning, anti-breakage strengthening, and anti-static flyaway reduction with shared controls and labor to reduce costs by up to 57%. The company is accepting participants until Aug. 15, 2010.
Jun 8, 2010
CeeTox has acquired assets of ADMETRx Inc. that allow it to expand its range of in vitro service offerings. Specifically, the acquired assets allow CeeTox to increase its existing Absorption, Distribution, Metabolism, Excretion (ADME) capabilities.
Jun 2, 2010
Researchers at the National Institute for Occupational Safety and Health and Portland State University have developed an animal-alternative test method to assess the potential for chemicals in consumer products to cause skin allergies.
May 27, 2010 | P. Ziosi, S. Manfredini, S. Vertuani, V. Ruscetta, M. Radice and G. Sacchetti, Università Degli Studi di Ferrara; and R. Bruni, Università Degli Studi di Parma
In the present work, the antioxidant capacities of three essential oils derived from basil and thyme were evaluated using a photochemiluminescence (PCL)-based assay. In addition, since the base formulation can affect the antioxidant activity of oils contained therein, ingredient interactions within final formulations were investigated.
Apr 30, 2010 | Leigh A. Belcher, Carl F. Muska, PhD, and Joseph W. DeSalvo, DuPont
In the present article, the authors assess the skin irritation and sensitization potential of 1,3-propanediol (INCI: Propanediol). Results in animals and humans by acute or repeat exposure support a low potential of skin reactivity for the material. In addition, the skin reactivity potential in humans was found to be lower with 1,3-propanediol than 1,2-propanediol (INCI: Propylene Glycol).
Mar 30, 2010 | Sara Farahmand, PhD, University of Cincinnati College of Pharmacy; and Howard I. Maibach, MD, PhD, University of California School of Medicine
While previous algorithms for predicting the skin absorption of permeants was based on in vitro data, the present article proposes a quantitative structure-activity relationship (QSAR) model based on in vivo human data. Here, a set of human in vivo data is described that provides entry into predicting the penetration of cosmetic ingredients.
Mar 16, 2010 | Johann W. Wiechers, PhD, JW Solutions
Six questions from Michael Shermer’s Baloney Detection Kit have been discussed in this series. The results were not flattering for cosmetic science (read: cosmetic scientists) but cosmetic science did not score badly on all points. Questions seven and eight, described here, discriminate true science from borderland science and non-science or nonsense.
Feb 26, 2010 | Ali Alikhan, MD, and Howard I. Maibach, MD
In this article, several methods to quantify the protein collected by tape stripping are described, including traditional gravimetric methods as well as novel colorimetric and visible spectroscopic techniques. Further, one colorimetric method is described to effectively determine the keratolytic efficacy of various materials in vivo, suggesting additional roles for this method.
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Between The Covers Discover:
- Amino acid distribution and biochemistry
- Examination of strength and anti-breakage product claims
- Hair: growth cycle, heat protection, shine, and color intensity and retention
- Overview of shampoos and issues relating to surfactants
- Science of hair color including chemical reactions and formulations
- Ethnic differences in hair and absorption of materials
- Evaluate and quantify visual properties of hair
- Dandruff-Causes and biology of the condition
- Hair styling products and polymers
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Finally! This book offers practical approach to the formulation chemist’s day-to-day endeavors by: addressing the innumerable challenges facing the chemist both in design and at bench, such as formulating with/for specific properties; offering valuable “tips” to troubleshooting issues regarding ingredient selection and interaction, regulatory concerns that must be addressed early in development, and the extrapolation of preservative systems; exploring the advantages and limitations of raw materials; addressing scale-up and pilot production process and concerns; and much more.Order your copy today.