Most Popular in Testing
- In vivo Delivery Confirmation: Measuring the Deposition of Salicylic Acid from Anti-acne Face Wash
- Phthalates Study Raises More Concerns, ‘But Who Cares?’
- Wet Skin Factor for Sunscreens: An In vitro Method, Part I
- Wet Skin Factor for Sunscreens: An In vitro Method, Part II
- 'Zapping' Sensitive Skin: Capsaicin Tests Show Embelia concinna Comforts Irritation
- VIDEO: P&G Scientists on Claims Substantiation in Anti-dandruff Care
- Evaluating 1,3-Propanediol for Potential Skin Effects
- How to Prove 'Rub-resistant' Sun Protection
- Antiaging in a Different Light: Assessing How Chromophores Color Perception
- Zeta Potential and Particle Size to Predict Emulsion Stability
Recent in Testing (page 15 of 32)
May 6, 2013 | Anthony J. Ribaudo, Textile Research Institute (TRI) Princeton
Here, the author compares two methods to determine the maturity of corneocytes based on their cross-linking that could be used to evaluate the anti-aging effects of molecular agents. The first utilizes microfluorometry, while the second involves F-D curves generated via contact mode AFM. Both methods successfully detected differences in mature or immature corneocytes with 95% confidence.
May 6, 2013 | Trefor Evans, PhD, TA Evans LLC
It should perhaps go without saying that consumer products are sold using consumer language. Market researchers and consumer scientists spend a great deal of time studying their target audience and learning this vocabulary, which subsequently allows the recounting of product benefits in the same terminology.
May 1, 2013
In the present work, the antioxidant capacities of three essential oils derived from basil and thyme were evaluated using a photochemiluminescence (PCL)-based assay. In addition, since the base formulation can affect the antioxidant activity of oils contained therein, ingredient interactions within final formulations were investigated.
May 1, 2013
In the present article, the authors assess the skin irritation and sensitization potential of 1,3-propanediol (INCI: Propanediol). Results in animals and humans by acute or repeat exposure support a low potential of skin reactivity for the material. In addition, the skin reactivity potential in humans was found to be lower with 1,3-propanediol than 1,2-propanediol (INCI: Propylene Glycol).
Apr 24, 2013
While previous algorithms for predicting the skin absorption of permeants was based on in vitro data, the present article proposes a quantitative structure-activity relationship (QSAR) model based on in vivo human data. Here, a set of human in vivo data is described that provides entry into predicting the penetration of cosmetic ingredients.
Apr 19, 2013
The Hurel Corp. has developed a microfluidic, non-animal alternative to the LLNA and it has partnered with L’Oréal to make this approach a reality—in the form of a chip.
Apr 19, 2013
In this article, several methods to quantify the protein collected by tape stripping are described, including traditional gravimetric methods as well as novel colorimetric and visible spectroscopic techniques. Further, one colorimetric method is described to effectively determine the keratolytic efficacy of various materials in vivo, suggesting additional roles for this method.
Apr 17, 2013
New methodologies have recently been developed to determine antioxidant effects but they often require extensive training and are time-consuming to conduct. In the present article, however, the authors describe an in vitro method to detect the effects of antioxidant-containing formulations using photochemiluminescence to provide rapid, accurate and sensitive measurements.
Apr 12, 2013
Researchers from the University of Aveiro, the University of Coimbra and the University Hospital of Coimbra have developed a dendritic cell-based test for skin sensitizers that can serve as an alternative to animal testing.
Apr 9, 2013
Beiersdorf has created a new method of skin analysis to help it develop new skin care products.
Apr 4, 2013
This work studies the applicability of a 96-well-based skin-mimetic artificial membrane permeability model to differentiate between topical pharmaceutical and cosmetic formulations. Results are compared with data obtained from in vitro Franz cell permeability measurements and reveal the applicability of this method to assess cosmetic formulation permeation and speed the discovery process.
Apr 4, 2013
Current in vitro methods to assess photostability and antioxidant activity do not account for the diffuse reflectance of skin. Described here is an in vitro test that addresses this variable, mimics end-use product conditions and models photodamage processes. The approach is employed to determine the efficacy of an antioxidant from the Camellia sinensis (tea) plant.